SCHEMBL6440577

SCHEMBL6440577

OC(C(F)(F)F)(C(F)(F)F)C(F)(F)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6054075 0.77 THRB (0.35)
SCHEMBL6152249 0.77 THRB (0.35)
SCHEMBL2459778 0.74
SCHEMBL266764 0.74
SCHEMBL25354322 0.70
SCHEMBL9292444 0.70
Potassium SCHEMBL30146709 0.70
SCHEMBL14473736 0.70
SCHEMBL28945780 0.70
SCHEMBL30959718 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1201628-B1 Electrophilic fluorination AIR PROD & CHEM (US) 2005-12-14 EP disclosed
EP-1201627-B1 Ring fluorination of non-activated aromatic compounds AIR PROD & CHEM (US) 2005-12-14 EP disclosed
EP-1201658-B1 N-Fluorotriazinium fluorinating agents AIR PROD & CHEM (US) 2005-08-03 EP disclosed
US-6737525-B2 USEFUL IN FLUORINATING, PREFERABLY IN A NITROMETHANE SOLVENT, CARBANIONIC SPECIES AND/OR ACTIVATED AROMATIC COMPOUNDS AIR PRODUCTS AND CHEMICALS, INC. 2004-05-18 US disclosed
US-6664391-B2 N-fluorotriazinium fluorinating agents AIR PRODUCTS AND CHEMICALS, INC. 2003-12-16 US disclosed
US-6635760-B2 Fluorinating a substrate selected from unsubstituted aromatic compounds and aromatic compounds having electron withdrawing substituent(s) comprises contacting substrate with a tri(halo or trifluoromethyl) substituted N-fluorotriazinium salt AIR PRODUCTS AND CHEMICALS, INC. 2003-10-21 US disclosed
US-20020123627-A1 N-fluorotriazinium fluorinating agents AIR PRODUCTS AND CHEMICALS, INC. 2002-09-05 US disclosed
US-20020123657-A1 Electrophilic fluorination AIR PRODUCTS AND CHEMICALS, INC. 2002-09-05 US disclosed
US-20020055662-A1 Ring fluorination of non-activated aromatic compounds AIR PRODUCTS AND CHEMICALS, INC. 2002-05-09 US disclosed
EP-1201658-A1 N-Fluorotriazinium fluorinating agents AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-05-02 EP disclosed
EP-1201627-A1 Ring fluorination of non-activated aromatic compounds AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-05-02 EP disclosed
EP-1201628-A1 Electrophilic fluorination AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-05-02 EP disclosed
US-5892035-A FLUORINATING THE CORRESPONDING DIAZABICYCLOALKALINE COMPOUND DAIKIN INDUSTRIES LTD. (JP) 1999-04-06 US disclosed
US-5672426-A LIQUID CRYSTAL POLYMER FROM P-HYDROXYBENZOIC ACID, HYDROQUINONE, ISOPHTHALIC ACID HOECHST CELANESE CORP (US) 1997-09-30 US disclosed
EP-0785199-A1 PROCESSES FOR PRODUCING N,N'-DIFLUORODIAZONIABICYCLO-ALKANE SALTS, INTERMEDIATES IN THE SYNTHESIS OF THE SAME, TARGET PRODUCTS, AND APPLICATION OF THE TARGET PRODUCTS DAIKIN INDUSTRIES, LIMITED (JP) 1997-07-23 EP disclosed
EP-0688812-A1 High barrier transparent films HOECHST CELANESE CORPORATION (US) 1995-12-27 EP disclosed
EP-0483850-B1 Process for producing salts of fluorinated alcohols AUSIMONT SPA (IT) 1995-08-09 EP disclosed
US-5227539-A PROCESS FOR PRODUCING SALTS OF FLUORINATED ALCOHOLS AUSIMONT S.P.A. (IT) 1993-07-13 US disclosed
EP-0483850-A2 Process for producing salts of fluorinated alcohols AUSIMONT S.p.A. (IT) 1992-05-06 EP disclosed