Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 10/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.73 |
| ▸ | RAB9A | P51151 | 8/20 | 0.73 |
| ▸ | NPC1 | O15118 | 6/20 | 0.73 |
| ▸ | HTT | P42858 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | STAT3 | P40763 | 1/20 | 0.73 |
| ▸ | GFER | P55789 | 3/20 | 0.65 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.65 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.65 |
| ▸ | KDM4A | O75164 | 5/20 | 0.64 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL6440584 | 1.00 | MEN1 (0.73) | MEN1KMT2ARAB9ANPC1HTT | |
| Bromide SCHEMBL8666504 | 0.97 | MEN1 (0.69) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL1080978 | 0.86 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL10843575 | 0.85 | MEN1 (0.56) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL10843581 | 0.85 | MEN1 (0.56) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL15587185 | 0.85 | MEN1 (0.67) | MEN1KMT2ARAB9ANPC1HTT | |
| Iodide SCHEMBL285058 | 0.85 | MEN1 (1.00) | MEN1KMT2ARAB9ANPC1HTT | |
| Iodide SCHEMBL29837406 | 0.85 | MEN1 (1.00) | MEN1KMT2ARAB9ANPC1HTT | |
| Iodide SCHEMBL285057 | 0.85 | MEN1 (1.00) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL3870022 | 0.83 | MEN1 (0.97) | MEN1KMT2ARAB9ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6966213-B2 | Rapid method for detecting leaks of hydraulic fluids in production plants | NALCO COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| US-20050160795-A1 | Rapid method for detecting leaks of hydraulic fluids in production plants | ECOLAB USA INC. | 2005-07-28 | — | — | US | disclosed |