Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 10/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 10/20 | 1.00 |
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | STAT3 | P40763 | 1/20 | 1.00 |
| ▸ | KDM4A | O75164 | 5/20 | 0.72 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.72 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.70 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.70 |
| ▸ | GFER | P55789 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 3/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL285057 | 1.00 | MEN1 (1.00) | MEN1KMT2ARAB9ANPC1HTT | |
| Iodide SCHEMBL29837406 | 1.00 | MEN1 (1.00) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL3870022 | 0.98 | MEN1 (0.97) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL3385183 | 0.98 | MEN1 (0.97) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL140215 | 0.90 | KMT2A (0.82) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL29681553 | 0.90 | KMT2A (0.82) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL140214 | 0.90 | KMT2A (0.82) | MEN1KMT2ARAB9ANPC1HTT | |
| SCHEMBL21005773 | 0.87 | KDM4A (0.81) | MEN1KMT2ARAB9ANPC1HTT | |
| Iodide SCHEMBL7024146 | 0.87 | MEN1 (0.77) | MEN1KMT2ARAB9ANPC1HTT | |
| Iodide SCHEMBL7024143 | 0.87 | MEN1 (0.77) | MEN1KMT2ARAB9ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014122370-A1 | METHOD FOR PURIFYING CELLS | SCHUSSLER OLIVIER (FR) | 2014-08-14 | — | — | WO | claimed |
| US-20140120564-A1 | NON-INVASIVE MEASUREMENT OF ANALYTES | CERCACOR LABORATORIES, INC. (US) | 2014-05-01 | — | — | US | claimed |
| US-8509867-B2 | Non-invasive measurement of analytes | CERCACOR LABORATORIES, INC. (US) | 2013-08-13 | — | — | US | claimed |
| US-20070020181-A1 | Non-invasive measurement of analytes | CERCACOR LABORATORIES, INC. | 2007-01-25 | — | — | US | claimed |
| EP-1200051-B1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KGAA (DE) | 2006-02-01 | — | — | EP | claimed |
| US-6966213-B2 | Rapid method for detecting leaks of hydraulic fluids in production plants | NALCO COMPANY (US) | 2005-11-22 | — | — | US | claimed |
| US-20050160795-A1 | Rapid method for detecting leaks of hydraulic fluids in production plants | ECOLAB USA INC. | 2005-07-28 | — | — | US | claimed |
| US-20040106163-A1 | Non-invasive measurement of analytes | MASIMO LABORATORIES, INC. | 2004-06-03 | — | — | US | claimed |
| WO-2004044557-A2 | NON-INVASIVE MEASUREMENT OF ANALYTES | ARGOSE, INC. (US) | 2004-05-27 | — | — | WO | claimed |
| EP-1200051-A1 | AGENT FOR DYING KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-05-02 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| US-5441795-A | Piperazinium compounds | XEROX CORPORATION (US) | 1995-08-15 | — | — | US | claimed |
| EP-0615855-A1 | Recording sheets containing pyridinium and/or piperazinum compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | claimed |
| US-4362645-A | Temperature indicating compositions of matter | AKZONA, INC. (US) | 1982-12-07 | — | — | US | claimed |
| US-4345470-A | All plastic disposable thermometer | AKZONA INCORPORATED (US) | 1982-08-24 | — | — | US | claimed |
| US-4339207-A | Temperature indicating compositions of matter | AKZONA INCORPORATED (US) | 1982-07-13 | — | — | US | claimed |
| US-4299727-A | Disposable reversible thermometer | AKZONA INCORPORATED (US) | 1981-11-10 | — | — | US | claimed |
| US-4232552-A | THERMOCHROMISM, DISPOSABLE THERMOMETERS | AKZONA INCORPORATED (US) | 1980-11-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070020181-A1 | Non-invasive measurement of analytes | SLC2A3, SLC2A2, SLC2A4 | ACHE 1971/4885MEN1 419/4885KMT2A 3930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.