Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507123 | 0.86 | HPGD (0.67) | HPGDHSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL157366 | 0.86 | HRH3 (0.53) | SMN1; SMN2RAB9ANPC1LMNATDP1 | |
| SCHEMBL30890579 | 0.85 | HPGD (0.65) | HPGDHSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL9416024 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1LMNATDP1 | |
| SCHEMBL9415918 | 0.84 | TAS1R3 (0.55) | SMN1; SMN2RAB9ANPC1LMNATDP1 | |
| SCHEMBL5697922 | 0.84 | KCNA5 (0.54) | HPGDHSD17B10SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9691525 | 0.83 | HPGD (0.56) | HPGDHSD17B10SMN1; SMN2ACHERAB9A | |
| SCHEMBL9695155 | 0.83 | HPGD (0.56) | HPGDHSD17B10SMN1; SMN2ACHERAB9A | |
| SCHEMBL9695556 | 0.83 | HPGD (0.56) | HPGDHSD17B10SMN1; SMN2ACHERAB9A | |
| SCHEMBL9694059 | 0.83 | HPGD (0.56) | HPGDHSD17B10SMN1; SMN2ACHERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501807-A1 | SULFONYLQUINOXALONE ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ ANTAGONISTS | Elan Pharmaceuticals, Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093245-A1 | SULFONYLQUINOXALONE ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS, INC. (US) | 2003-11-13 | — | — | WO | disclosed |