Gitoxigenin

Gitoxigenin

SCHEMBL644087

C[C@]12CC[C@H](O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C3=CC(=O)OC3)[C@@H](O)C[C@]12O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 7/20 1.00
RAB9A P51151 4/20 1.00
CYP2C19 P33261 2/20 1.00
ATP1A1 P05023 7/20 0.74
ATP1B1 P05026 7/20 0.74
ATP1A3 P13637 7/20 0.74
ATP1B2 P14415 7/20 0.74
ATP1A2 P50993 7/20 0.74
ATP1B3 P54709 7/20 0.74
FXYD2 P54710 7/20 0.74
ATP1A4 Q13733 7/20 0.74
SMN1; SMN2 Q16637 4/20 0.74
PAX8 Q06710 3/20 0.74
LMNA P02545 3/20 0.74
NPC1 O15118 3/20 0.74
HIF1A Q16665 2/20 0.74
CYP3A4 P08684 1/20 0.74
TSHR P16473 1/20 0.74
ATP12A P54707 1/20 0.74
SLCO4C1 Q6ZQN7 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gitoxigenin SCHEMBL3302691 1.00 TP53 (1.00) TP53RAB9ACYP2C19ATP1A1ATP1B1
Gitoxigenin SCHEMBL13338042 1.00 TP53 (1.00) TP53RAB9ACYP2C19ATP1A1ATP1B1
Gitoxigenin SCHEMBL19638184 1.00 TP53 (1.00) TP53RAB9ACYP2C19ATP1A1ATP1B1
Gitoxigenin SCHEMBL8417147 1.00 TP53 (1.00) TP53RAB9ACYP2C19ATP1A1ATP1B1
Gitoxigenin SCHEMBL3302694 1.00 TP53 (1.00) TP53RAB9ACYP2C19ATP1A1ATP1B1
SCHEMBL14681100 0.88 TP53 (0.79) TP53RAB9ACYP2C19ATP1A1ATP1B1
SCHEMBL4905625 0.88 TP53 (0.84) TP53RAB9ACYP2C19ATP1A1ATP1B1
SCHEMBL17864015 0.88 TP53 (0.84) TP53RAB9ACYP2C19ATP1A1ATP1B1
SCHEMBL11408235 0.87 TP53 (0.77) TP53RAB9ACYP2C19ATP1A1ATP1B1
SCHEMBL21578190 0.87 TP53 (0.77) TP53RAB9ACYP2C19ATP1A1ATP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024259191-A2 METHOD AND COMPOSITIONS FOR TREATING SKIN DISORDERS PHOENIX BIOTECHNOLOGY, INC. (US) 2024-12-19 WO claimed
US-12097234-B2 Extract containing oleandrin and method of production thereof PHOENIX BIOTECHNOLOGY, INC. (US) 2024-09-24 US claimed
US-20240261312-A1 Method and compositions for treating animal viral infections PHOENIX BIOTECHNOLOGY, INC. (US) 2024-08-08 US claimed
EP-4387627-A1 METHOD AND COMPOSITIONS FOR TREATING ANIMAL VIRAL INFECTIONS Phoenix Biotechnology, Inc. (US) 2024-06-26 EP claimed
EP-4295854-A2 METHOD AND COMPOSITIONS FOR TREATING CORONAVIRUS INFECTION Phoenix Biotechnology, Inc. (US) 2023-12-27 EP claimed
WO-2023239747-A2 METHODS OF MODULATING ATXN2 EXPRESSION UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2023-12-14 WO claimed
WO-2023235807-A2 METHOD AND COMPOSITIONS FOR TREATING GLIOBLASTOMA WITH TRITERPENES PHOENIX BIOTECHNOLOGY, INC. (US) 2023-12-07 WO claimed
US-11806359-B2 Method and compositions for treating Coronavirus infection PHOENIX BIOTECHNOLOGY, INC. (US) 2023-11-07 US claimed
US-20230158093-A1 Extract containing oleandrin and method of production thereof PHOENIX BIOTECHNOLOGY, INC. (US) 2023-05-25 US claimed
WO-2023022866-A1 METHOD AND COMPOSITIONS FOR TREATING ANIMAL VIRAL INFECTIONS PHOENIX BIOTECHNOLOGY, INC. (US) 2023-02-23 WO claimed
JP-2921989-B2 1999-07-19 JP claimed
US-5804371-A HAPTEN-ACTIVE ESTER DERIVATIVE IS COUPLED TO A FREE PRIMARY AMINO GROUP OF THE PEPTIDE BOEHRINGER MANNHEIM GMBH (DE) 1998-09-08 US claimed
CN-1130910-A Hapten-labelled peptides BOEHRINGER MANNHEIM GMBH (DE) 1996-09-11 CN claimed
EP-0723551-A1 HAPTEN-MARKED PEPTIDES Roche Diagnostics GmbH (DE) 1996-07-31 EP claimed
WO-1996003423-A9 HAPTEN-MARKED PEPTIDES 1996-03-07 WO claimed
WO-1996003423-A1 HAPTEN-MARKED PEPTIDES BOEHRINGER MANNHEIM GMBH (DE) 1996-02-08 WO claimed
EP-0341745-B1 Crosslinked carboxy polysaccharides FIDIA SPA (IT) 1994-12-14 EP claimed
EP-0614914-A2 Crosslinked carboxy polysaccharides FIDIA S.p.A. (IT) 1994-09-14 EP claimed
US-4011212-A 22-CYANO-24-NORCHOLANES AMERICAN HOME PRODUCTS CORPORATION (US) 1977-03-08 US claimed
US-3944541-A 22-Cyano-24-norcholanes AMERICAN HOME PRODUCTS CORPORATION (US) 1976-03-16 US claimed