Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45045 | 0.89 | SQLE (0.32) | TDP1ALDH1A1CYP3A4CYP2D6MAPT | |
| SCHEMBL445817 | 0.89 | SQLE (0.32) | TDP1ALDH1A1CYP3A4CYP2D6MAPT | |
| Benzene SCHEMBL28183857 | 0.87 | ALDH1A1 (0.32) | EP300ALDH1A1CYP3A4CYP2D6MAPT | |
| SCHEMBL3337401 | 0.83 | SQLE (0.33) | TDP1 | |
| SCHEMBL3337399 | 0.83 | SQLE (0.33) | TDP1 | |
| SCHEMBL443349 | 0.83 | SQLE (0.34) | EP300ALDH1A1CYP3A4CYP2D6MAPT | |
| SCHEMBL443348 | 0.83 | SQLE (0.34) | EP300ALDH1A1CYP3A4CYP2D6MAPT | |
| Methacrylic Acid SCHEMBL316586 | 0.81 | TDP1 (0.41) | TDP1 | |
| Methacrylic Acid SCHEMBL9251534 | 0.81 | TDP1 (0.34) | TDP1ALDH1A1CYP2D6 | |
| SCHEMBL9321713 | 0.81 | EP300 (0.35) | EP300ALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210093-A4 | DEGRADABLE POLYMERS | POLYTHERICS LTD (GB) | 2005-01-12 | — | — | EP | claimed |
| EP-1210093-A1 | DEGRADABLE POLYMERS | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2002-06-05 | — | — | EP | claimed |
| WO-2001017515-A1 | DEGRADABLE POLYMERS | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2001-03-15 | — | — | WO | claimed |
| EP-1210093-A4 | DEGRADABLE POLYMERS | POLYTHERICS LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6828412-B1 | Degradable polymers | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2004-12-07 | — | — | US | disclosed |
| EP-1210093-A1 | DEGRADABLE POLYMERS | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001017515-A1 | DEGRADABLE POLYMERS | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2001-03-15 | — | — | WO | disclosed |