Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4940887 | 0.71 | SOAT1 (0.41) | ALDH1A1ALOX15MAPT | |
| SCHEMBL6440514 | 0.70 | — | — | |
| SCHEMBL6441213 | 0.70 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1085238 | 0.67 | ALDH1A1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL942071 | 0.65 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2001451 | 0.65 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2199236 | 0.64 | GAA (0.38) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL2197500 | 0.64 | GAA (0.40) | ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL9376935 | 0.63 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL4481930 | 0.62 | TP53 (0.37) | ALDH1A1MEN1KMT2ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066237-B1 | PROCESSES FOR PREPARING INTERMEDIATES | BAYER CROPSCIENCE SA (FR) | 2005-07-20 | — | — | EP | disclosed |
| US-6642418-B1 | 1,3-dione compounds from beta keto esters | AVENTIS CROPSCIENCE SA (FR) | 2003-11-04 | — | — | US | disclosed |
| EP-1066237-A2 | PROCESSES FOR PREPARING INTERMEDIATES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999048851-A2 | PROCESSES FOR PREPARING INTERMEDIATES | AVENTIS CROPSCIENCE S.A. (FR) | 1999-09-30 | — | — | WO | disclosed |