Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3868775 | 0.87 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL6441090 | 0.87 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL3872814 | 0.86 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL3863213 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3869713 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL3864347 | 0.84 | PTGS2 (0.83) | PTGS2PTGS1 | |
| SCHEMBL3865180 | 0.84 | PTGS2 (0.83) | PTGS2PTGS1 | |
| SCHEMBL3867770 | 0.83 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL3865233 | 0.79 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL3865904 | 0.79 | PTGS2 (0.71) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534683-A4 | CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED INC (US) | 2005-08-24 | — | — | EP | disclosed |
| EP-1534683-A2 | CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE | Nitromed, Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004002409-A2 | CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2004-01-08 | — | — | WO | disclosed |