Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.57 |
| ▸ | ITGAV | P06756 | 15/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439782 | 0.86 | ITGB3 (0.57) | ITGB3ITGAVHSD17B10NPC1RAB9A | |
| SCHEMBL6440168 | 0.84 | ITGB3 (0.67) | ITGB3ITGAVHSD17B10 | |
| SCHEMBL6441642 | 0.82 | ITGB3 (0.53) | ITGB3ITGAVPDE10A | |
| SCHEMBL6439267 | 0.78 | AURKA (0.37) | ITGB3ITGAVHSD17B10PDE10A | |
| SCHEMBL6445908 | 0.75 | ITGB3 (0.58) | ITGB3ITGAVNPC1RAB9ATP53 | |
| SCHEMBL6444230 | 0.74 | ITGB3 (0.68) | ITGB3ITGAVHSD17B10TP53 | |
| SCHEMBL6424300 | 0.73 | ITGB3 (0.72) | ITGB3ITGAV | |
| SCHEMBL5026328 | 0.72 | ITGB3 (0.70) | ITGB3ITGAV | |
| SCHEMBL5028419 | 0.72 | ITGB3 (1.00) | ITGB3ITGAV | |
| SCHEMBL5028370 | 0.72 | ITGB3 (1.00) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |