Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6441617 | 1.00 | APP (0.40) | APPKDM4EMEN1CYP1A2RECQL | |
| SCHEMBL6441625 | 1.00 | APP (0.40) | APPKDM4EMEN1CYP1A2RECQL | |
| SCHEMBL6442559 | 0.88 | LMNA (0.39) | KDM4EKMT2AHSD17B10F2RL3 | |
| SCHEMBL6442566 | 0.88 | LMNA (0.39) | KDM4EKMT2AHSD17B10F2RL3 | |
| SCHEMBL6442562 | 0.88 | LMNA (0.39) | KDM4EKMT2AHSD17B10F2RL3 | |
| SCHEMBL6445516 | 0.80 | FGFR1 (0.42) | KDM4EMEN1CYP1A2KMT2AHSD17B10 | |
| SCHEMBL6445522 | 0.80 | FGFR1 (0.42) | KDM4EMEN1CYP1A2KMT2AHSD17B10 | |
| SCHEMBL6445527 | 0.80 | FGFR1 (0.42) | KDM4EMEN1CYP1A2KMT2AHSD17B10 | |
| SCHEMBL6441834 | 0.77 | PDE4D (0.36) | KDM4EMEN1KMT2AHSD17B10PDE3A | |
| SCHEMBL6441838 | 0.77 | PDE4D (0.36) | KDM4EMEN1KMT2AHSD17B10PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303506-B1 | 6-HETEROARYLPHENANTHRIDINES | ALTANA PHARMA AG (DE) | 2005-02-02 | — | — | EP | claimed |
| US-6884802-B2 | 6-heteroarylphenanthridines | ALTANA PHARMA AG (DE) | 2005-04-26 | — | — | US | disclosed |
| EP-1303506-B1 | 6-HETEROARYLPHENANTHRIDINES | ALTANA PHARMA AG (DE) | 2005-02-02 | — | — | EP | disclosed |
| US-20040038979-A1 | Treating airway disorders such as asthma. | ALTANA PHARMA AG (DE) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038979-A1 | Treating airway disorders such as asthma. | PTGER4, PDE4B, PDE4A | APP 4429/4885KDM4E 2186/4885MEN1 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.