Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | GMNN | O75496 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15820927 | 0.95 | GPR84 (0.46) | TSHRHPGDCYP1A2MAPK1GMNN | |
| SCHEMBL10913590 | 0.94 | GPR84 (0.49) | TSHRHPGDCYP1A2MAPK1GMNN | |
| SCHEMBL27700851 | 0.88 | TSHR (0.54) | TSHRHPGDMAPK1ACHEBACE1 | |
| SCHEMBL2129127 | 0.84 | TSHR (0.51) | TSHRHPGDMAPK1ACHEBACE1 | |
| SCHEMBL1398238 | 0.84 | TSHR (0.56) | TSHRHPGDMAPK1ACHEBACE1 | |
| SCHEMBL7864075 | 0.84 | TSHR (0.51) | TSHRHPGDMAPK1MAPTGPR84 | |
| SCHEMBL31456184 | 0.83 | TSHR (0.50) | TSHRHPGDMAPK1MAPTGPR84 | |
| SCHEMBL7537024 | 0.83 | TSHR (0.50) | TSHRHPGDMAPK1MAPTGPR84 | |
| SCHEMBL31742396 | 0.83 | TSHR (0.50) | TSHRHPGDMAPK1MAPTGPR84 | |
| SCHEMBL11060479 | 0.83 | TSHR (0.50) | TSHRHPGDMAPK1MAPTCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1182189-B1 | Process for recovering butyl acrylate substantially free from acrylic acid | ROHM & HAAS (US) | 2005-03-09 | — | — | EP | disclosed |
| US-6506930-B1 | Charging reactor with C1-C4 alcohol, (meth)acrylic acid, strong acid catalyst, inhibitor and water to form mixture, reacting to form a C1-C4 alkyl (meth) acrylate and process impurities which are hydrolyzed, separating ester and water | ROHM AND HAAS COMPANY | 2003-01-14 | — | — | US | disclosed |
| EP-0779268-B1 | Process for producing alkyl acrylate | ROHM & HAAS (US) | 2002-06-19 | — | — | EP | disclosed |
| EP-1182189-A2 | Process for recovering butyl acrylate substantially free from acrylic acid | ROHM AND HAAS COMPANY (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-0916643-B1 | A process for preparing alkyl (meth)acrylates | ROHM & HAAS (US) | 2001-12-19 | — | — | EP | disclosed |
| US-6180819-B1 | DISTILLING FROM ESTERIFICATION REACTOR VAPORIZED MIXTURE OF ACRYLIC ACID, ALKYL ACRYLATE, ALKANOL AND WATER, SEPARATING ORGANIC AND AQUEOUS PHASES, FEEDING TO ACRYLIC ACID SEPARATION COLUMN, DISTILLING AZEOTROPE MIXTURE, SEPARATING ESTER | ROHM AND HAAS COMPANY | 2001-01-30 | — | — | US | disclosed |
| EP-0916643-A1 | A process for preparing alkyl (meth)acrylates | ROHM AND HAAS COMPANY (US) | 1999-05-19 | — | — | EP | disclosed |
| EP-0779268-A1 | Process for producing alkyl acrylate | ROHM AND HAAS COMPANY (US) | 1997-06-18 | — | — | EP | disclosed |