Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 9/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28093702 | 0.82 | THRB (0.40) | TSHRHPGDTHRBTHRACYP3A4 | |
| SCHEMBL15821018 | 0.81 | TSHR (0.47) | TSHRHPGDTHRBATMHCAR2 | |
| SCHEMBL29372293 | 0.80 | TSHR (0.50) | TSHRHPGDTHRBATMHCAR2 | |
| SCHEMBL3234096 | 0.80 | TSHR (0.50) | TSHRHPGDTHRBATMHCAR2 | |
| SCHEMBL28780914 | 0.80 | TSHR (0.50) | TSHRHPGDTHRBATMHCAR2 | |
| SCHEMBL28345184 | 0.79 | TSHR (0.48) | TSHRHPGDTHRBATMTHRA | |
| SCHEMBL31609320 | 0.78 | TSHR (0.52) | TSHRHPGDTHRBATMHCAR2 | |
| SCHEMBL28853858 | 0.78 | TSHR (0.35) | TSHRHPGDTHRBTHRACYP3A4 | |
| SCHEMBL15618963 | 0.78 | GAA (0.52) | TSHRATMHCAR2ALDH1A1FDPS | |
| SCHEMBL17023949 | 0.78 | GAA (0.52) | TSHRATMHCAR2ALDH1A1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1182189-B1 | Process for recovering butyl acrylate substantially free from acrylic acid | ROHM & HAAS (US) | 2005-03-09 | — | — | EP | disclosed |
| US-6506930-B1 | Charging reactor with C1-C4 alcohol, (meth)acrylic acid, strong acid catalyst, inhibitor and water to form mixture, reacting to form a C1-C4 alkyl (meth) acrylate and process impurities which are hydrolyzed, separating ester and water | ROHM AND HAAS COMPANY | 2003-01-14 | — | — | US | disclosed |
| EP-0779268-B1 | Process for producing alkyl acrylate | ROHM & HAAS (US) | 2002-06-19 | — | — | EP | disclosed |
| EP-1182189-A2 | Process for recovering butyl acrylate substantially free from acrylic acid | ROHM AND HAAS COMPANY (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-0916643-B1 | A process for preparing alkyl (meth)acrylates | ROHM & HAAS (US) | 2001-12-19 | — | — | EP | disclosed |
| US-6180819-B1 | DISTILLING FROM ESTERIFICATION REACTOR VAPORIZED MIXTURE OF ACRYLIC ACID, ALKYL ACRYLATE, ALKANOL AND WATER, SEPARATING ORGANIC AND AQUEOUS PHASES, FEEDING TO ACRYLIC ACID SEPARATION COLUMN, DISTILLING AZEOTROPE MIXTURE, SEPARATING ESTER | ROHM AND HAAS COMPANY | 2001-01-30 | — | — | US | disclosed |
| EP-0916643-A1 | A process for preparing alkyl (meth)acrylates | ROHM AND HAAS COMPANY (US) | 1999-05-19 | — | — | EP | disclosed |
| EP-0779268-A1 | Process for producing alkyl acrylate | ROHM AND HAAS COMPANY (US) | 1997-06-18 | — | — | EP | disclosed |