Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28878299 | 0.79 | CMA1 (0.46) | AHRCMA1TGM2CES1GABRA1 | |
| SCHEMBL6441771 | 0.74 | NPC1 (0.52) | AHRMAPTCYP1A2TSHRDDB1 | |
| SCHEMBL1764573 | 0.73 | AHR (0.70) | AHRCMA1PKMSRD5A1PGR | |
| SCHEMBL11412815 | 0.71 | AHR (0.49) | AHRCMA1TGM2CES1PGR | |
| SCHEMBL30435230 | 0.70 | AHR (0.66) | AHRCMA1PKMSRD5A1PGR | |
| SCHEMBL6959254 | 0.70 | AHR (0.51) | AHRCMA1TGM2CES1PKM | |
| SCHEMBL1184405 | 0.70 | TGM2 (0.53) | AHRCMA1TGM2CES1PKM | |
| SCHEMBL7492910 | 0.70 | AHR (0.66) | AHRCMA1PKMSRD5A1PGR | |
| SCHEMBL2395389 | 0.69 | AHR (0.70) | AHRCMA1PKMSRD5A1MAOA | |
| SCHEMBL29754265 | 0.69 | AHR (0.70) | AHRCMA1PKMSRD5A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |