Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260651 | 0.93 | CES2 (0.48) | CES2CES1MEN1ALDH1A1LMNA | |
| SCHEMBL10710779 | 0.90 | CES2 (0.43) | CES2CES1 | |
| SCHEMBL10710744 | 0.81 | CES2 (0.56) | CES2CES1HTT | |
| SCHEMBL11263582 | 0.75 | CES2 (0.56) | CES2CES1LMNAHTT | |
| SCHEMBL9511320 | 0.75 | CES2 (0.34) | CES2CES1 | |
| SCHEMBL10608746 | 0.73 | CES2 (0.33) | CES2CES1 | |
| SCHEMBL9693234 | 0.73 | CES2 (0.42) | CES2CES1 | |
| SCHEMBL27689767 | 0.72 | CES2 (0.46) | CES2CES1MEN1ALDH1A1LMNA | |
| SCHEMBL10709506 | 0.71 | CES2 (0.46) | CES2CES1 | |
| SCHEMBL11255943 | 0.71 | CES2 (0.52) | CES2CES1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233010-B1 | Method for production of organic fluorine compound | NIPPON CATALYTIC CHEM IND (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-0899256-B1 | Method for production of organic fluorine compound | NIPPON CATALYTIC CHEM IND (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-1233010-A1 | Method for production of organic fluorine compound | Nippon Shokubai Co., Ltd. (JP) | 2002-08-21 | — | — | EP | disclosed |
| US-6437168-B1 | FLUORINATION; EFFICIENT EXTRACTION | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |
| US-6392084-B1 | FLUORINATION OF AN ORGANO(BROMINE OR CHLORIDE) COMPOUND IN BENZONITRILE SOLVENT | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| US-20020035301-A1 | Method for production of aromatic fluorine compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-03-21 | — | — | US | disclosed |
| EP-0899256-A2 | Method for production of organic fluorine compound | NIPPON SHOKUBAI CO., LTD. (JP) | 1999-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035301-A1 | Method for production of aromatic fluorine compound | AFF4, AFF2, AFF1 | CES2 355/4885CES1 2953/4885MEN1 2142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.