SCHEMBL6442304

SCHEMBL6442304

C=CCCc1ccc(-c2ccc3c(F)c(-c4cc(F)c(OC)c(F)c4)ccc3c2)cc1.C=CCOc1ccc(-c2ccc3cc(-c4ccc(CC)cc4)ccc3c2F)cc1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MGAM O43451 4/20 0.36
GAA P10253 4/20 0.36
SI P14410 4/20 0.36
MGAM2 Q2M2H8 4/20 0.36
MAOB P27338 2/20 0.33
GRM2 Q14416 1/20 0.32
MAOA P21397 1/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3266266 0.88 ESR1 (0.36) MAOBGRM2
SCHEMBL6060182 0.87 MAOB (0.35) MGAMGAASIMGAM2MAOB
SCHEMBL3154003 0.86 MAOB (0.36) MGAMGAASIMGAM2MAOB
SCHEMBL3153695 0.83 ESR1 (0.36)
SCHEMBL6059440 0.82 MAOB (0.35) MGAMGAASIMGAM2MAOB
SCHEMBL3167520 0.82 THRB (0.37) MGAMGAASIMGAM2MAOB
SCHEMBL3165455 0.82 GRM2 (0.36) GRM2FFAR1
SCHEMBL3172539 0.82 MAOB (0.36) MGAMGAASIMGAM2MAOB
SCHEMBL3153870 0.82 MAOB (0.39) MAOBGRM2FFAR1
SCHEMBL3162516 0.82 ESR1 (0.40) GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0952135-B1 Naphthalene derivative and liquid crystal composition comprising the same DAINIPPON INK & CHEMICALS (JP) 2005-01-05 EP disclosed