Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.82 |
| ▸ | MAPT | P10636 | 9/20 | 0.82 |
| ▸ | IDH1 | O75874 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12316787 | 0.94 | KMT2A (0.82) | MEN1KMT2AMAPTIDH1MAPK1 | |
| SCHEMBL8345735 | 0.88 | MEN1 (0.70) | MEN1KMT2AMAPTMAPK1TP53 | |
| SCHEMBL13556626 | 0.87 | KMT2A (0.71) | MEN1KMT2AMAPTIDH1MAPK1 | |
| SCHEMBL6441408 | 0.86 | MAPT (0.76) | MEN1KMT2AMAPTMAPK1TP53 | |
| SCHEMBL6442532 | 0.85 | KMT2A (0.62) | MEN1KMT2AMAPTIDH1MAPK1 | |
| SCHEMBL7824229 | 0.85 | KMT2A (0.68) | MEN1KMT2AMAPTIDH1MAPK1 | |
| SCHEMBL10221504 | 0.84 | MEN1 (0.67) | MEN1KMT2AMAPTIDH1MAPK1 | |
| SCHEMBL6442535 | 0.82 | GAA (0.67) | MEN1KMT2AMAPTGAAPOLB | |
| SCHEMBL23485744 | 0.82 | KMT2A (0.64) | MEN1KMT2AMAPTIDH1MAPK1 | |
| SCHEMBL13556615 | 0.81 | MAPT (0.60) | MEN1KMT2AMAPTMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1148048-B1 | Polyaromatic compounds for treating herpes viral infections | PHARMACIA & UPJOHN CO LLC (US) | 2005-06-29 | — | — | EP | claimed |
| EP-1148048-A2 | Polyaromatic antiviral compositions | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-24 | — | — | EP | claimed |
| US-6147116-A | TOPICALLY ADMINISTERING BENZENE DERIVATIVE SUBSTITUTED WITH UREIDO-, THIOUREIDO, AND/OR SULFONAMIDO GROUPS TO TREAT HERPES | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-14 | — | — | US | claimed |
| EP-1148048-B1 | Polyaromatic compounds for treating herpes viral infections | PHARMACIA & UPJOHN CO LLC (US) | 2005-06-29 | — | — | EP | disclosed |
| EP-1148048-A2 | Polyaromatic antiviral compositions | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-24 | — | — | EP | disclosed |
| US-6147116-A | TOPICALLY ADMINISTERING BENZENE DERIVATIVE SUBSTITUTED WITH UREIDO-, THIOUREIDO, AND/OR SULFONAMIDO GROUPS TO TREAT HERPES | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-14 | — | — | US | disclosed |
| US-5958983-A | NOVEL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST HERPES, TOPICAL ADMINISTRATION THEM TO TREAT PATIENTS WITH HERPES; WORK BY INHIBITING THE INITIATION OF HERPES VIRAL DNA SYNTHESIS IN HOST CELLS | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-28 | — | — | US | disclosed |