Fluoride

Fluoride

SCHEMBL6442891

F.O=C(O)c1ccccc1F

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.65
CES1 P23141 2/20 0.65
ALDH1A1 P00352 5/20 0.62
ALOX15 P16050 2/20 0.62
ALB P02768 1/20 0.61
GAA P10253 1/20 0.54
PTPN1 P18031 1/20 0.53
ERCC5 P28715 1/20 0.53
FEN1 P39748 1/20 0.53
HPGD P15428 3/20 0.52
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA4 P22748 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
NAPRT Q6XQN6 2/20 0.52
KDM4E B2RXH2 1/20 0.52
HMGB1 P09429 1/20 0.52
CA6 P23280 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362443 0.97 CES2 (0.68) CES2CES1ALDH1A1ALOX15ALB
SCHEMBL30968201 0.97 CES2 (0.68) CES2CES1ALDH1A1ALOX15ALB
SCHEMBL97828 0.97 CES2 (0.68) CES2CES1ALDH1A1ALOX15ALB
SCHEMBL9015790 0.95 CES2 (0.65) CES2CES1ALDH1A1ALOX15ALB
Hydrochloric Acid SCHEMBL6592453 0.95 CES2 (0.65) CES2CES1ALDH1A1ALOX15ALB
Hydrochloric Acid SCHEMBL23201659 0.95 CES2 (0.65) CES2CES1ALDH1A1ALOX15ALB
SCHEMBL28208054 0.95 CES2 (0.65) CES2CES1ALDH1A1ALOX15ALB
SCHEMBL10357059 0.95 CES2 (0.65) CES2CES1ALDH1A1ALOX15ALB
SCHEMBL11451385 0.95 CES2 (0.65) CES2CES1ALDH1A1ALOX15ALB
Ammonia Solution, Strong SCHEMBL27732698 0.95 CES2 (0.65) CES2CES1ALDH1A1ALOX15ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233010-B1 Method for production of organic fluorine compound NIPPON CATALYTIC CHEM IND (JP) 2005-06-15 EP disclosed
EP-0899256-B1 Method for production of organic fluorine compound NIPPON CATALYTIC CHEM IND (JP) 2003-08-06 EP disclosed
EP-1233010-A1 Method for production of organic fluorine compound Nippon Shokubai Co., Ltd. (JP) 2002-08-21 EP disclosed
US-6392084-B1 FLUORINATION OF AN ORGANO(BROMINE OR CHLORIDE) COMPOUND IN BENZONITRILE SOLVENT NIPPON SHOKUBAI CO., LTD. (JP) 2002-05-21 US disclosed
EP-0899256-A2 Method for production of organic fluorine compound NIPPON SHOKUBAI CO., LTD. (JP) 1999-03-03 EP disclosed