SCHEMBL6443212

SCHEMBL6443212

CCCCOc1ncc(S(=O)(=O)N2CCN(CC)CC2)cc1-c1nc2c(CC)n(CC)nc2c(=O)[nH]1

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 20/20 0.85
PDE6C P51160 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6444754 0.96 PDE5A (0.87) PDE5APDE6C
SCHEMBL6443570 0.94 PDE5A (0.77) PDE5APDE6C
SCHEMBL3583701 0.93 PDE5A (0.93) PDE5APDE6C
SCHEMBL6447389 0.93 PDE5A (0.91) PDE5APDE6C
SCHEMBL13500475 0.93 PDE5A (0.85) PDE5APDE6C
SCHEMBL3580414 0.92 PDE5A (1.00) PDE5A
SCHEMBL3586558 0.91 PDE5A (0.80) PDE5APDE6C
SCHEMBL3579775 0.90 PDE5A (0.88) PDE5A
SCHEMBL6446212 0.90 PDE5A (0.86) PDE5A
SCHEMBL6446034 0.89 PDE5A (0.89) PDE5APDE6C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1371647-B1 Pyridine-3-carboxylic acid derivatives and their use as intermediates PFIZER (US) 2005-07-13 EP disclosed