⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917688 | 0.75 | — | — | |
| SCHEMBL14138735 | 0.73 | — | — | |
| SCHEMBL20100699 | 0.72 | — | — | |
| SCHEMBL18237410 | 0.71 | — | — | |
| SCHEMBL7567155 | 0.70 | — | — | |
| SCHEMBL13317702 | 0.70 | — | — | |
| SCHEMBL20981454 | 0.70 | — | — | |
| SCHEMBL27415570 | 0.70 | — | — | |
| SCHEMBL12081976 | 0.68 | DAPK3 (0.32) | — | |
| SCHEMBL15012245 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104105714-B | Prepare the method and thus obtained product of acrylate copolymer | 路博润高级材料公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-1867733-A | Fibrous structures exhibiting improved wet strength properties | PROCTER & GAMBLE (US) | 2006-11-22 | — | — | CN | disclosed |
| US-20050130941-A1 | Methods of treating alzheimer's disease | PHARMACIA & UPJOHN COMPANY LLC | 2005-06-16 | — | — | US | disclosed |
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| WO-2002077709-A2 | PHOTORESIST COMPOSITION | SHIPLEY COMPANY, L.L.C. (US) | 2002-10-03 | — | — | WO | disclosed |
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0521827-B1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA GEIGY AG (CH) | 1996-09-25 | — | — | EP | disclosed |
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
| EP-0092255-B1 | COMPOSITE TYPE PHOTOSENSITIVE MEMBER FOR ELECTROPHOTOGRAPHY | HITACHI, LTD. (JP) | 1987-01-14 | — | — | EP | disclosed |