Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.71 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.63 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MMP14 | P50281 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30213377 | 0.86 | AKR1C3 (0.72) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL355486 | 0.86 | AKR1C3 (0.72) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL10935935 | 0.86 | MEN1 (0.60) | MEN1KMT2APKMSIRT2MAPT | |
| SCHEMBL9409067 | 0.84 | AKR1C3 (0.60) | MEN1KMT2APKMSIRT2MAPT | |
| SCHEMBL28357281 | 0.84 | SIRT2 (0.75) | SIRT2MAPK10KDM4ERECQLRAB9A | |
| SCHEMBL10515711 | 0.83 | MEN1 (0.65) | MEN1KMT2APKMMAPTKDM4E | |
| SCHEMBL10990122 | 0.83 | MEN1 (0.61) | MEN1KMT2APKMMAPK10MAPT | |
| SCHEMBL15688476 | 0.82 | SIRT2 (0.71) | MEN1KMT2ASIRT2MAPTKDM4E | |
| SCHEMBL294128 | 0.82 | AKR1C3 (0.78) | — | |
| SCHEMBL10983702 | 0.82 | MEN1 (0.56) | MEN1KMT2APKMSIRT2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107325019-B | Aryl amine benzamide compound and N- aryl-aryl amine benzamide compound preparation method | 石河子大学 | 2019-11-22 | — | — | CN | disclosed |
| CN-107325019-A | The preparation method of aryl amine benzamide compound and N aryl aryl amine benzamide compounds | 石河子大学 | 2017-11-07 | — | — | CN | disclosed |
| EP-2505198-A1 | Compounds for use as therapeutic agents affecting p53 expression and/or activity | Société Splicos (FR) | 2012-10-03 | — | — | EP | disclosed |
| EP-1517897-A2 | BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS ESTROGEN AGONISTS/ANTAGONISTS | Pfizer Products Inc. (US) | 2005-03-30 | — | — | EP | disclosed |
| US-20040002524-A1 | Benzimidazole compounds and their use as estrogen agonists/antagonists | CHESWORTH RICHARD (US) | 2004-01-01 | — | — | US | disclosed |
| WO-2004000817-A2 | BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS ESTROGEN AGONISTS/ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2003-12-31 | — | — | WO | disclosed |
| US-4549016-A | LIPOXYGENASE INHIBITORS, ANTIALLERGENS, ANTIASTHMA AGENTS | STERLING DRUG INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4510139-A | ANTYIALLERGENS; ASTHMA | STERLING DRUG INC. (US) | 1985-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002524-A1 | Benzimidazole compounds and their use as estrogen agonists/antagonists | ESR1, GPER1, ESR2 | MEN1 4482/4885KMT2A 1738/4885PKM 1691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.