Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 10/20 | 0.72 |
| ▸ | AKR1C2 | P52895 | 10/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.67 |
| ▸ | FABP4 | P15090 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30213377 | 1.00 | AKR1C3 (0.72) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| Isopropyl Alcohol SCHEMBL11691639 | 0.94 | AKR1C3 (0.65) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL10935935 | 0.87 | MEN1 (0.60) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL1963433 | 0.86 | AKR1C3 (0.62) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL18109767 | 0.86 | FABP4 (0.85) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL14598923 | 0.86 | AKR1C3 (0.78) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL6443532 | 0.86 | MEN1 (0.72) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL9501833 | 0.85 | MAPT (0.68) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL28676345 | 0.85 | MEN1 (0.72) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL10990122 | 0.84 | MEN1 (0.61) | AKR1C3AKR1C2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105476992-A | Application of 2-methoxy-9-acridine benzamido thiourea in preparation of acetylcholinesterase inhibitor | UNIV GUANGXI CHINESE MEDICINE | 2016-04-13 | — | — | CN | claimed |
| WO-2023242688-A1 | OPHTHALMIC DEVICES CONTAINING PHOTOSTABLE MIMICS OF MACULAR PIGMENT AND OTHER VISIBLE LIGHT FILTERS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| CN-111057004-B | N-o-substituted phenyl benzamide-4-methylaminoacridine compound and preparation method and application thereof | 宁波大学 | 2023-10-31 | — | — | CN | disclosed |
| CN-109988106-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine | 广东东阳光药业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115698190-A | Photostable simulation of macular pigment | 强生视力健公司 | 2023-02-03 | — | — | CN | disclosed |
| WO-2022130089-A1 | PHOTOSTABLE MIMICS OF MACULAR PIGMENT | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2022-06-23 | — | — | WO | disclosed |
| US-20220194944-A1 | PHOTOSTABLE MIMICS OF MACULAR PIGMENT | JOHNSON & JOHNSON VISION CARE, INC. | 2022-06-23 | — | — | US | disclosed |
| EP-3315028-B1 | USE OF INHIBITORS OF NLP PROTEINS AS PHYTOPHARMACEUTICALS FOR PLANT PATHOGEN CONTROL | KEMIJSKI INST (SI) | 2020-09-02 | — | — | EP | disclosed |
| EP-3315028-B1 | USE OF INHIBITORS OF NLP PROTEINS AS PHYTOPHARMACEUTICALS FOR PLANT PATHOGEN CONTROL | KEMIJSKI INST (SI) | 2020-09-02 | — | — | EP | disclosed |
| CN-111057004-A | N-ortho-substituted phenyl benzamide-4-methylaminoacridine compound and preparation method and application thereof | 宁波大学 | 2020-04-24 | — | — | CN | disclosed |
| US-4629735-A | ANTIASTHMATIC AGENTS | STERLING DRUG INC. (US) | 1986-12-16 | — | — | US | disclosed |
| EP-0186367-A2 | Acidic indole compounds and their use as antiallergy agents | WARNER-LAMBERT COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4549016-A | LIPOXYGENASE INHIBITORS, ANTIALLERGENS, ANTIASTHMA AGENTS | STERLING DRUG INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4515980-A | LIPOXYGENASE INHIBITORS | STERLING DRUG INC. (US) | 1985-05-07 | — | — | US | disclosed |
| US-4510139-A | ANTYIALLERGENS; ASTHMA | STERLING DRUG INC. (US) | 1985-04-09 | — | — | US | disclosed |
| US-4168312-A | Quinolone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-09-18 | — | — | US | disclosed |
| US-4058532-A | 1-Phenyl-3,4-dihydrocarbostyrils | STERLING DRUG INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4049715-A | 3-[2-(4-Anisidino)phenyl]-1-phenyl-1-propiophenones and propanols | STERLING DRUG INC. (US) | 1977-09-20 | — | — | US | disclosed |
| US-4021470-A | LUBRICANT STABILIZERS | MOBIL OIL CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |
| US-3994902-A | Certain 1,2-diphenyl-1,2,3,4-tetrahydroquinoline compounds | STERLING DRUG INC. (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220194944-A1 | PHOTOSTABLE MIMICS OF MACULAR PIGMENT | CRY1, PDE6C, PDE6A | AKR1C3 3394/4885AKR1C2 3689/4885MAPT 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.