Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | GHSR | Q92847 | 7/20 | 0.42 |
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1763938 | 0.91 | CYP2D6 (0.70) | CYP2C9CYP2D6CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL1763941 | 0.91 | CYP2D6 (0.70) | CYP2C9CYP2D6CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL2688411 | 0.88 | CYP2C9 (1.00) | CYP2C9CYP2D6CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL30966670 | 0.88 | CYP2C9 (1.00) | CYP2C9CYP2D6CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL1763665 | 0.87 | CYP2D6 (0.65) | CYP2C9CYP2D6CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL12198757 | 0.86 | CYP2D6 (0.64) | CYP2C9CYP2D6CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL1763782 | 0.86 | CYP2D6 (0.64) | CYP2C9CYP2D6CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL4072420 | 0.86 | CYP2D6 (0.64) | CYP2C9CYP2D6CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL1763048 | 0.86 | CYP2D6 (0.63) | CYP2C9CYP2D6CYP2C19CYP3A4CYP1A2 | |
| SCHEMBL1763196 | 0.86 | CYP2D6 (0.63) | CYP2C9CYP2D6CYP2C19CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900323-B2 | Antiviral azaindole derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-05-31 | — | — | US | disclosed |
| US-20040023982-A1 | Antiviral azaindole derivatives | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2004-02-05 | — | — | US | disclosed |
| US-6476034-B2 | AIDS THERAPY | BRISTOL-MYERS SQUIBB COMPANY | 2002-11-05 | — | — | US | disclosed |
| US-20020119982-A1 | Antiviral azaindole derivatives | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119982-A1 | Antiviral azaindole derivatives | ZC3HAV1, MAVS, AZI2 | CYP2C9 3477/4885CYP2D6 1648/4885CYP2C19 3101/4885 |
| US-20040023982-A1 | Antiviral azaindole derivatives | ZC3HAV1, MAVS, EIF2AK2 | CYP2C9 3466/4885CYP2D6 1508/4885CYP2C19 3009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.