SCHEMBL6443734

SCHEMBL6443734

O=C(Oc1ccccc1[N+](=O)[O-])OC(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 2/20 0.47
CYP1A2 P05177 2/20 0.47
MAPT P10636 1/20 0.47
CYP2C9 P11712 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.46
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
RECQL P46063 1/20 0.46
ESR2 Q92731 1/20 0.45
HTT P42858 1/20 0.44
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
POLB P06746 3/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL18955379 0.84 ALDH1A1 (0.56) ALDH1A1MEN1KMT2ATDP1CYP1A2
Bicarbonate SCHEMBL18955378 0.84 ALDH1A1 (0.56) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL17627881 0.84 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL57736 0.84 ALDH1A1 (0.60) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL29911025 0.84 ALDH1A1 (0.60) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL8134133 0.83 ALDH1A1 (0.53) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL10335049 0.81 ALDH1A1 (0.51) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL983419 0.81 ALDH1A1 (0.62) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL6257741 0.81 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL5164726 0.81 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ATDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0506830-B1 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES AVI BIOPHARMA INC (US) 2005-12-14 EP disclosed
EP-0962463-B1 Uncharged morpholino-based polymers having phosphorus-containing chiral intersubunit linkages ANTIVIRALS INC (US) 2002-07-10 EP disclosed
EP-0962463-A1 Uncharged morpholino-based polymers having phosphorus-containing chiral intersubunit linkages ANTIVIRALS INC. (US) 1999-12-08 EP disclosed
EP-0506845-B1 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING ACHIRAL INTERSUBUNIT LINKAGES ANTIVIRALS INC (US) 1998-03-18 EP disclosed
US-5521063-A Polynucleotide reagent containing chiral subunits and methods of use ANTIVIRALS INC. (US) 1996-05-28 US disclosed
US-5185444-A Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages ANTI-GENE DEVEOPMENT GROUP (US) 1993-02-09 US disclosed
EP-0506830-A4 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES 1993-01-07 EP disclosed
EP-0506845-A4 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING ACHIRAL INTERSUBUNIT LINKAGES 1992-10-21 EP disclosed
EP-0506845-A1 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING ACHIRAL INTERSUBUNIT LINKAGES ANTIVIRALS INC. (US) 1992-10-07 EP disclosed
EP-0506830-A1 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES ANTIVIRALS INC. (US) 1992-10-07 EP disclosed
US-5034506-A Polymers for the determination of genetic sequences and viral diseases ANTI-GENE DEVELOPMENT GROUP (US) 1991-07-23 US disclosed
WO-1991009073-A1 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING ACHIRAL INTERSUBUNIT LINKAGES ANTI-GENE DEVELOPMENT GROUP (US) 1991-06-27 WO disclosed
WO-1991009033-A1 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES ANTI-GENE DEVELOPMENT GROUP (US) 1991-06-27 WO disclosed