SCHEMBL6443748

SCHEMBL6443748

CCC(Cc1c(C(=O)O)ccc(C(=O)O)c1CC(CC)CC(C)C)CC(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
RAB9A P51151 2/20 0.36
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ACE P12821 1/20 0.35
CYP1A2 P05177 1/20 0.34
CACNA2D1 P54289 2/20 0.34
CACNB3 P54284 1/20 0.34
CACNA1C Q13936 1/20 0.34
PGR P06401 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
CACNA2D2 Q9NY47 1/20 0.34
TRPA1 O75762 1/20 0.34
POLB P06746 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2852934 0.84 POLB (0.32) ALDH1A1RAB9AKDM4EMEN1KMT2A
SCHEMBL1950367 0.79 CYP1A2 (0.44) ALDH1A1KDM4ECYP1A2AKR1C2AKR1C1
SCHEMBL6451346 0.78 MAPT (0.42) ALDH1A1RAB9AKDM4EMEN1KMT2A
SCHEMBL621545 0.78 ALDH1A1 (0.48) ALDH1A1KDM4EMEN1KMT2AMAPK1
SCHEMBL27208711 0.76 ALDH1A1 (0.41) ALDH1A1KDM4EMEN1KMT2AMAPK1
SCHEMBL27208713 0.75 ALDH1A1 (0.40) ALDH1A1KDM4EMAPK1GABRPGABRD
SCHEMBL27208716 0.74 PPARA (0.40) ALDH1A1KDM4EMAPK1GABRPGABRD
SCHEMBL10779747 0.74 CYP1A2 (0.39) ALDH1A1RAB9AKDM4EMEN1KMT2A
SCHEMBL6902769 0.74 CYP1A2 (0.42) ALDH1A1RAB9AKDM4EMEN1KMT2A
SCHEMBL6444382 0.73 POLB (0.39) ALDH1A1RAB9AKDM4ECYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1194396-B1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AG (DE) 2005-11-09 EP claimed
EP-1194396-A1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2002-04-10 EP claimed
WO-2000078704-A1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2000-12-28 WO claimed
EP-1194396-B1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AG (DE) 2005-11-09 EP disclosed