Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443801 | 1.00 | LMNA (0.41) | LMNAKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL6441413 | 0.90 | LMNA (0.44) | LMNAKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL6441410 | 0.90 | LMNA (0.44) | LMNAKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL6444068 | 0.87 | GRIN2D (0.40) | LMNAKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL6442702 | 0.85 | HPGD (0.44) | LMNAKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL6442705 | 0.85 | HPGD (0.44) | LMNAKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL6441474 | 0.84 | LMNA (0.48) | LMNAKMT2AMAPTHPGDKDM4E | |
| SCHEMBL6443312 | 0.84 | LMNA (0.48) | LMNAKMT2AMAPTHPGDKDM4E | |
| SCHEMBL6441478 | 0.84 | LMNA (0.48) | LMNAKMT2AMAPTHPGDKDM4E | |
| SCHEMBL6443315 | 0.84 | LMNA (0.48) | LMNAKMT2AMAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894190-B2 | Process for producing optically active 3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid, and salt thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-17 | — | — | US | disclosed |