Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.81 |
| ▸ | PPARG | P37231 | 7/20 | 0.81 |
| ▸ | PPARD | Q03181 | 7/20 | 0.81 |
| ▸ | PPARA | Q07869 | 7/20 | 0.81 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.81 |
| ▸ | TSHR | P16473 | 4/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | FABP4 | P15090 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.81 |
| ▸ | TLR2 | O60603 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.81 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.81 |
| ▸ | ESR1 | P03372 | 1/20 | 0.81 |
| ▸ | PDE4A | P27815 | 1/20 | 0.81 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL9443646 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Lignoceric Acid SCHEMBL9985280 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL9443618 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL29105360 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL9233233 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL10341818 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL15876102 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL9984027 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL9443627 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL11457951 | 0.98 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115418008-A | Industrial production method of color master batch | 长兴科隆新材料科技有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-108779972-A | The bullet of compacting mixture including copper powders | 辛特范尔公司 | 2018-11-09 | — | — | CN | claimed |
| CN-118126440-A | Ultra-high sun-proof anti-aging PE (polyethylene) plate and preparation method thereof | 佳贺科技无锡有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-115418008-A | Industrial production method of color master batch | 长兴科隆新材料科技有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-107531995-A | Resin combination and its products formed | 东丽株式会社 | 2018-01-02 | — | — | CN | disclosed |
| CN-105637034-B | Amilan polyamide resin composition, manufacture method, products formed | 东丽株式会社 | 2017-06-30 | — | — | CN | disclosed |
| EP-1002022-B2 | GRANULAR COMPACTS, THEIR PRODUCTION AND USE | CLARIANT FINANCE BVI LTD (VG) | 2005-05-04 | — | — | EP | disclosed |
| US-6712862-B1 | STORAGE STABILITY; MIXING WATER-SOLUBLE DYE OR OPTICAL BRIGHTENER WITH EXTENDER AND HYDROPHILIC SURFACTANT; DRY-COMPACTING, GRANULATION; TREATING WITH DUST-BINDING OIL | CLARIANT FINANCE (BVI) LIMITED (VG) | 2004-03-30 | — | — | US | disclosed |
| EP-1002022-B1 | GRANULAR COMPACTS, THEIR PRODUCTION AND USE | CLARIANT FINANCE BVI LTD (VG) | 2002-06-12 | — | — | EP | disclosed |
| EP-1002022-A1 | GRANULAR COMPACTS, THEIR PRODUCTION AND USE | Clariant Finance (BVI) Limited (VG) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999005226-A1 | GRANULAR COMPACTS, THEIR PRODUCTION AND USE | CLARIANT FINANCE (BVI) LIMITED (VG) | 1999-02-04 | — | — | WO | disclosed |
| EP-0509149-B1 | Thermal dye sublimation transfer receiving element | AGFA GEVAERT NV (BE) | 1996-03-13 | — | — | EP | disclosed |
| US-5284815-A | Image-receiving layer containing an isocyanate-based polymer having a crosslinked and cured surface; dyeability; releasability from the dye donor element | AGFA-GEVAERT, N.V. (BE) | 1994-02-08 | — | — | US | disclosed |
| US-4142991-A | TITANIUM TRICHLORIDE | STAUFFER CHEMICAL COMPANY (US) | 1979-03-06 | — | — | US | disclosed |