Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34685 | 0.91 | TSHR (0.50) | TSHRHPGDATMHCAR2ALDH1A1 | |
| SCHEMBL11295941 | 0.87 | TSHR (0.40) | TSHRHPGDATMHCAR2ALDH1A1 | |
| Acrylonitrile SCHEMBL315873 | 0.86 | HCAR2 (0.51) | TSHRHPGDATMHCAR2ALDH1A1 | |
| Acrylic Acid SCHEMBL11555488 | 0.85 | TSHR (0.49) | TSHRHPGDATMHCAR2ALDH1A1 | |
| SCHEMBL28268344 | 0.85 | TSHR (0.57) | TSHRHPGDATMHCAR2ALDH1A1 | |
| Butadiene SCHEMBL9419686 | 0.84 | TSHR (0.47) | TSHRHPGDATMHCAR2ALDH1A1 | |
| SCHEMBL2259513 | 0.82 | ATM (0.50) | TSHRHPGDATMHCAR2ALDH1A1 | |
| SCHEMBL3320514 | 0.82 | TSHR (0.50) | TSHRHPGDATMHCAR2ALDH1A1 | |
| SCHEMBL250053 | 0.81 | HCAR2 (0.40) | TSHRHPGDATMHCAR2ALDH1A1 | |
| Acrylonitrile SCHEMBL3403014 | 0.81 | HCAR2 (0.54) | TSHRHPGDATMHCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933339-B2 | Nitrile rubber composition, vulcanizable nitrile rubber composition, and vulcanizate | ZEON CORPORATION (JP) | 2005-08-23 | — | — | US | disclosed |
| US-20030166789-A1 | Nitrile rubber composition, vulcanizable nitrile rubber composition, and vulcanizate | ZEON CORPORATION (JP) | 2003-09-04 | — | — | US | disclosed |
| US-4559390-A | BLEND OF UNSATURATED NITRILES, CONJUGATED DIENES AND OTHER UNSATURATED COMPOUNDS | NIPPON ZEON CO., LTD. (JP) | 1985-12-17 | — | — | US | disclosed |