SCHEMBL250053

SCHEMBL250053

C=CC=CC(=C)C(=O)OCCC

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.40
TSHR P16473 4/20 0.38
HPGD P15428 1/20 0.36
THRB P10828 1/20 0.35
ATM Q13315 1/20 0.34
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 3/20 0.32
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
APP P05067 1/20 0.30
ESR1 P03372 1/20 0.30
CHRM1 P11229 1/20 0.30
SLC6A2 P23975 1/20 0.30
KDR P35968 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL17746688 0.93 HCAR2 (0.43) HCAR2TSHRHPGDTHRBATM
SCHEMBL34685 0.89 TSHR (0.50) HCAR2TSHRHPGDTHRBATM
SCHEMBL28268344 0.86 TSHR (0.57) HCAR2TSHRHPGDATMALDH1A1
Ethyl Fumarate SCHEMBL1068462 0.85 HCAR2 (0.55) HCAR2TSHRHPGDTHRBATM
SCHEMBL250740 0.85 ALDH1A1 (0.42) HCAR2TSHRTHRBGAASMN1; SMN2
Acrylic Acid SCHEMBL11555488 0.84 TSHR (0.49) HCAR2TSHRHPGDATMALDH1A1
Acrylonitrile SCHEMBL6443897 0.81 TSHR (0.42) HCAR2TSHRHPGDATMALDH1A1
SCHEMBL22471936 0.81 HCAR2 (0.42) HCAR2TSHRHPGDTHRBATM
SCHEMBL7567247 0.80 TSHR (0.45) HCAR2TSHRHPGDTHRBATM
SCHEMBL3320514 0.80 TSHR (0.50) HCAR2TSHRHPGDTHRBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11331939-B2 Recording media HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-05-17 US claimed
US-20200301296-A1 EMULSION AGGREGATION PROCESS XEROX CORPORATION 2020-09-24 US claimed
US-20200180338-A1 RECORDING MEDIA HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2020-06-11 US claimed
EP-3266908-B1 ANTI-BACTERIAL METALLO IONOMER POLYMER NANOCOMPOSITE FILAMENTS AND METHODS OF MAKING THE SAME XEROX CORP (US) 2020-05-06 EP claimed
US-10570290-B2 Anti-bacterial aqueous ink compositions comprising metal ion composite ionomer resins XEROX CORPORATION (US) 2020-02-25 US claimed
US-10543707-B2 Recording media HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2020-01-28 US claimed
EP-3266613-B1 ANTI-BACTERIAL METALLO IONOMER POLYMER COMPOSITE POWDERS AND METHODS OF MAKING THE SAME XEROX CORP (US) 2019-10-16 EP claimed
US-10405540-B2 Anti-bacterial metallo ionomer polymer nanocomposite filaments and methods of making the same XEROX CORPORATION (US) 2019-09-10 US claimed
US-10113059-B2 Anti-bacterial metallo ionomer polymer nanocomposite powders and methods of making the same XEROX CORPORATION (US) 2018-10-30 US claimed
US-10067434-B2 Emulsion aggregation toners XEROX CORPORATION (US) 2018-09-04 US claimed
US-5928829-A Latex processes XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0928994-A2 Toner preparation processes Xerox Corporation (US) 1999-07-14 EP claimed
US-5869216-A LATEX, AGGREGATION, FUSION/COALESCENCE, SURFACE TREATMENT WITH A SALICYLIC ACID OR A CATECHOL XEROX CORPORATION (US) 1999-02-09 US claimed
US-5863698-A MIXING COLORANT COMPRISING PHOSPHATE-CONTAINING SURFACTANT, LATEX EMULSION, HEATING, STABILIZING XEROX CORPORATION (US) 1999-01-26 US claimed
US-5858601-A Toner processes XEROX CORPORATION (US) 1999-01-12 US claimed
US-5827633-A Toner processes XEROX CORPORATION (US) 1998-10-27 US claimed
US-5766818-A Toner processes with hydrolyzable surfactant XEROX CORPORATION (US) 1998-06-16 US claimed
US-5766817-A AGGREGATING COLORANT DISPERSION WITH LATEX MINIEMULSION CONTAINING POLYMER AND IONIC AND NONIONIC SURFACTANTS, COALESCING THE AGGREGATES GENERATED XEROX CORPORATION (US) 1998-06-16 US claimed
US-5763133-A Toner compositions and processes XEROX CORPORATION (US) 1998-06-09 US claimed
US-5747215-A Toner compositions and processes XEROX CORPORATION (US) 1998-05-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10113059-B2 Anti-bacterial metallo ionomer polymer nanocomposite powders and methods of making the same RPN1, RPN2, MSH2 HCAR2 4553/4885TSHR 4205/4885HPGD 1695/4885
US-10405540-B2 Anti-bacterial metallo ionomer polymer nanocomposite filaments and methods of making the same TERB1, NBAS, MFAP1 HCAR2 4392/4885TSHR 4098/4885HPGD 2095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.