SCHEMBL6443899

SCHEMBL6443899

CCC(C)(C)OCCCCl

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3290589 0.79 TSHR (0.41) TSHRTDP1ALDH1A1CA1CA2
SCHEMBL13283795 0.78
SCHEMBL13382670 0.78 TSHR (0.50) TSHRTDP1ALDH1A1
SCHEMBL29690437 0.77 ALDH1A1 (0.39) TSHRTDP1ALDH1A1
SCHEMBL9750843 0.77 TSHR (0.39) TSHRTDP1ALDH1A1CA1CA2
SCHEMBL30549094 0.77 ALDH1A1 (0.39) TSHRTDP1ALDH1A1
SCHEMBL1539183 0.76
SCHEMBL24400073 0.75 ALDH1A1 (0.38) TSHRTDP1ALDH1A1
SCHEMBL8024586 0.75 LPAR3 (0.41) TSHRTDP1ALDH1A1CA1CA2
SCHEMBL20476803 0.75 LPAR3 (0.41) TSHRTDP1ALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858679-B2 Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions FMC CORPORATION (US) 2005-02-22 US disclosed
EP-1028982-B1 COMPOSITIONS PROVIDING IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS AND PROCESSES FOR IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS FMC CORP (US) 2003-10-29 EP disclosed
US-20030153693-A1 Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions QUIRK RODERIC PAUL (US) 2003-08-14 US disclosed
US-6605564-B1 Anionic polymerization initiators and salt additives selected from sodium chloride, sodium iodide, potassium chloride, potassium t-butoxide, for increasing the efficiency of reactions between living polymer anions and electrophiles FMC CORPORATION 2003-08-12 US disclosed
US-6545103-B2 Living polymers FMC CORPORATION 2003-04-08 US disclosed
US-20020010082-A1 Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions FMC CORPORATION 2002-01-24 US disclosed
EP-1028982-A1 COMPOSITIONS PROVIDING IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS AND PROCESSES FOR IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS FMC CORPORATION (US) 2000-08-23 EP disclosed
WO-1999025740-A1 COMPOSITIONS PROVIDING IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS AND PROCESSES FOR IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS FMC CORPORATION (US) 1999-05-27 WO disclosed
EP-0746572-B1 NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORP (US) 1999-04-28 EP disclosed
US-5827929-A Functionalized initiators for anionic polymerization FMC CORPORATION (US) 1998-10-27 US disclosed
US-5792815-A CONJUGATED POLYENE OR ALKENYL SUBSTITUTED ARYL HYDROCARBON POLYMERS; MOLDING MATERIALS FMC CORPORATION (US) 1998-08-11 US disclosed
WO-1997024377-A1 FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORPORATION (US) 1997-07-10 WO disclosed
US-5621149-A REACTING AN OMEGA-PROTECTED-1-HALOALKYL WITH AN ALKALI METAL DISPERSION IN AN INERT HYDROCARBON SOLVENT FMC CORPORATION (US) 1997-04-15 US disclosed
EP-0746572-A4 NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORP (US) 1997-03-26 EP disclosed
US-5600021-A ORGANOMETALLIC COMPOUND CONTAINING ETHER GROUP FMC CORPORATION (US) 1997-02-04 US disclosed
EP-0746572-A1 NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORPORATION (US) 1996-12-11 EP disclosed
US-5567774-A USING SODIUM, POTASSIUM, OR LITHIUM HYDROCARBYL ETHER COMPOUNDS AS INITIATORS FMC CORPORATION (US) 1996-10-22 US disclosed
WO-1995022566-A1 NEW FUNCTIONALIZED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORPORATION (US) 1995-08-24 WO disclosed