Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.47 |
| ▸ | PTPRB | P23467 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4306665 | 0.89 | MEN1 (0.51) | MEN1KMT2ASTSJAK2JAK1 | |
| SCHEMBL4306307 | 0.88 | MEN1 (0.57) | MEN1KMT2ASTSJAK2JAK1 | |
| SCHEMBL4302400 | 0.87 | MEN1 (0.53) | MEN1KMT2ASTSJAK2JAK1 | |
| SCHEMBL4309350 | 0.85 | MEN1 (0.67) | MEN1KMT2ASTSJAK2JAK1 | |
| SCHEMBL4318763 | 0.84 | MEN1 (0.53) | MEN1KMT2ASTSJAK2JAK1 | |
| SCHEMBL4306235 | 0.84 | MEN1 (0.53) | MEN1KMT2ASTSJAK2JAK1 | |
| SCHEMBL4306735 | 0.84 | KMT2A (0.57) | MEN1KMT2ASTSJAK2JAK1 | |
| SCHEMBL4116057 | 0.83 | USP30 (0.46) | MEN1KMT2ASTSJAK2JAK1 | |
| SCHEMBL4239118 | 0.82 | GPR119 (0.56) | MEN1KMT2ASTSJAK2JAK1 | |
| SCHEMBL652408 | 0.81 | MEN1 (0.57) | MEN1KMT2ASTSJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556045-A1 | 4-AMINOPIPERIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB, S.A. (BE) | 2005-07-27 | — | — | EP | claimed |
| WO-2004030668-A1 | 4-AMINOPIPERIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB, S.A. (BE) | 2004-04-15 | — | — | WO | claimed |