Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443709 | 0.94 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1HTTSIGMAR1TSHR | |
| SCHEMBL11200677 | 0.88 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1HTTSIGMAR1TSHR | |
| SCHEMBL12064295 | 0.82 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTSIGMAR1TSHR | |
| SCHEMBL12064296 | 0.82 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTSIGMAR1TSHR | |
| SCHEMBL10181568 | 0.82 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTSIGMAR1TSHR | |
| SCHEMBL3119460 | 0.80 | S1PR1 (0.46) | TSHRS1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL5776683 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL30330329 | 0.80 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1HTTSIGMAR1TSHR | |
| Fluoride SCHEMBL30331161 | 0.80 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1HTTSIGMAR1TSHR | |
| SCHEMBL154109 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858679-B2 | Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions | FMC CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20030153693-A1 | Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions | QUIRK RODERIC PAUL (US) | 2003-08-14 | — | — | US | disclosed |
| US-6605564-B1 | Anionic polymerization initiators and salt additives selected from sodium chloride, sodium iodide, potassium chloride, potassium t-butoxide, for increasing the efficiency of reactions between living polymer anions and electrophiles | FMC CORPORATION | 2003-08-12 | — | — | US | disclosed |
| US-6545103-B2 | Living polymers | FMC CORPORATION | 2003-04-08 | — | — | US | disclosed |
| US-20020010082-A1 | Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions | FMC CORPORATION | 2002-01-24 | — | — | US | disclosed |
| US-6184338-B1 | USEFUL IN THE PREPARATION OF TERTIARY AMINE CONTAINING POLYMERS, INCLUDING LINEAR, HOMOTELECHELIC, HETEROTELECHELIC AND RADIAL POLYMERS. | FMC CORPORATION | 2001-02-06 | — | — | US | disclosed |
| US-4594428-A | Pyrrolidine compounds | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1986-06-10 | — | — | US | disclosed |
| EP-0024960-B1 | SUBSTITUTED HETEROCYCLIC PHENOXY AMINES, THEIR PREPARATION METHOD AND THEIR USE AS LOCAL ANAESTHETICS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1984-12-12 | — | — | EP | disclosed |
| US-4405623-A | HYPOTENSIVE AGENTS, VASODILATORS | MASAYUKI ISHIKAWA (JP) | 1983-09-20 | — | — | US | disclosed |
| US-4379161-A | Novel substituted heterocyclic phenoxyamines, the method of preparation thereof and the use thereof as local anaesthetics | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE FRANCE (FR) | 1983-04-05 | — | — | US | disclosed |
| EP-0024960-A2 | Substituted heterocyclic phenoxy amines, their preparation method and their use as local anaesthetics | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1981-03-11 | — | — | EP | disclosed |