Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273888 | 0.85 | HRH3 (0.49) | HRH3SMN1; SMN2HSD11B1HTR4GNAO1 | |
| SCHEMBL6445015 | 0.83 | GNAO1 (0.45) | HRH3HTR4GNAO1EPHX1EPHX2 | |
| SCHEMBL6444283 | 0.81 | SMN1; SMN2 (0.43) | HRH3SMN1; SMN2HSD11B1HTR4EPHX1 | |
| SCHEMBL28149564 | 0.81 | HRH3 (0.46) | HRH3SMN1; SMN2HSD11B1GNAO1EPHX1 | |
| SCHEMBL70799 | 0.81 | HRH3 (0.46) | HRH3SMN1; SMN2HSD11B1GNAO1EPHX1 | |
| SCHEMBL31273045 | 0.81 | HRH3 (0.46) | HRH3SMN1; SMN2HSD11B1GNAO1EPHX1 | |
| Hydrochloric Acid SCHEMBL30330895 | 0.79 | HRH3 (0.45) | HRH3SMN1; SMN2HSD11B1GNAO1EPHX1 | |
| Fluoride SCHEMBL29252579 | 0.79 | HRH3 (0.45) | HRH3SMN1; SMN2HSD11B1GNAO1EPHX1 | |
| SCHEMBL4383559 | 0.77 | SMN1; SMN2 (0.45) | HRH3SMN1; SMN2HSD11B1HTR4GNAO1 | |
| SCHEMBL12112146 | 0.77 | CYP1A2 (0.54) | HRH3SMN1; SMN2HSD11B1GNAO1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858679-B2 | Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions | FMC CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20030153693-A1 | Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions | QUIRK RODERIC PAUL (US) | 2003-08-14 | — | — | US | disclosed |
| US-6605564-B1 | Anionic polymerization initiators and salt additives selected from sodium chloride, sodium iodide, potassium chloride, potassium t-butoxide, for increasing the efficiency of reactions between living polymer anions and electrophiles | FMC CORPORATION | 2003-08-12 | — | — | US | disclosed |
| US-6545103-B2 | Living polymers | FMC CORPORATION | 2003-04-08 | — | — | US | disclosed |
| US-20020010082-A1 | Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions | FMC CORPORATION | 2002-01-24 | — | — | US | disclosed |
| US-6184338-B1 | USEFUL IN THE PREPARATION OF TERTIARY AMINE CONTAINING POLYMERS, INCLUDING LINEAR, HOMOTELECHELIC, HETEROTELECHELIC AND RADIAL POLYMERS. | FMC CORPORATION | 2001-02-06 | — | — | US | disclosed |