Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798444 | 0.86 | EZH2 (0.33) | CRHR1EZH2 | |
| SCHEMBL6799993 | 0.85 | EZH2 (0.33) | CRHR1EZH2 | |
| SCHEMBL6794382 | 0.84 | CRHR1 (0.35) | CRHR1EZH2 | |
| SCHEMBL6798933 | 0.82 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL6799272 | 0.81 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL6798762 | 0.81 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL6798056 | 0.80 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL5844028 | 0.79 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL6802282 | 0.79 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL5844263 | 0.78 | CRHR1 (0.41) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |