Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 6/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023972 | 0.85 | PDE2A (0.52) | PDE2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6024102 | 0.77 | PDE2A (0.47) | PDE2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6023204 | 0.76 | PDE2A (0.51) | PDE2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6023289 | 0.74 | PDE2A (0.47) | PDE2AKDM4EALDH1A1HPGDPDE4A | |
| SCHEMBL6023837 | 0.73 | PDE2A (0.51) | PDE2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6023710 | 0.69 | PDE2A (0.47) | PDE2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6023361 | 0.69 | PDE2A (0.45) | PDE2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7354927 | 0.68 | PDE2A (0.57) | PDE2AALDH1A1HPGDCDK4CCND1 | |
| SCHEMBL6023263 | 0.67 | PDE2A (0.44) | PDE2A | |
| SCHEMBL6024717 | 0.67 | PDE2A (0.46) | PDE2AKDM4EALDH1A1HPGDPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601675-A1 | PURIN-6-ONE-DERIVATIVES | ALTANA Pharma AG (DE) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004089953-A1 | PURIN-6-ONE-DERIVATIVES | ALTANA PHARMA AG (DE) | 2004-10-21 | — | — | WO | disclosed |