SCHEMBL6445994

SCHEMBL6445994

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nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
ALOX15 P16050 2/20 0.53
BLM P54132 2/20 0.53
PMP22 Q01453 1/20 0.53
NOD1 Q9Y239 10/20 0.48
FOLH1 Q04609 2/20 0.40
GLO1 Q04760 1/20 0.40
PTGS1 P23219 1/20 0.39
GSTK1 Q9Y2Q3 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
NFKB1 P19838 1/20 0.39
PTGS2 P35354 1/20 0.39
THPO P40225 1/20 0.39
RECQL P46063 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GRM8 O00222 1/20 0.39
GRM6 O15303 1/20 0.39
GRIN2D O15399 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL8764303 0.91 KMT2A (0.63) KMT2AALOX15BLMPMP22NOD1
Glutamine SCHEMBL29150368 0.91 KMT2A (0.63) KMT2AALOX15BLMPMP22NOD1
Glutamine SCHEMBL8764294 0.91 KMT2A (0.63) KMT2AALOX15BLMPMP22NOD1
Glutamine SCHEMBL8764292 0.91 KMT2A (0.63) KMT2AALOX15BLMPMP22NOD1
SCHEMBL24978671 0.85 MAPT (0.52) ALOX15BLMNOD1FOLH1KDM4E
SCHEMBL24978634 0.85 MAPT (0.52) ALOX15BLMNOD1FOLH1KDM4E
SCHEMBL24978653 0.85 MAPT (0.52) ALOX15BLMNOD1FOLH1KDM4E
SCHEMBL12964807 0.84 KMT2A (0.66) KMT2AALOX15BLMPMP22NOD1
SCHEMBL236266 0.84 KMT2A (0.66) KMT2AALOX15BLMPMP22NOD1
SCHEMBL236265 0.84 KMT2A (0.66) KMT2AALOX15BLMPMP22NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1555896-A1 METHODS AND COMPOSITIONS FOR PROVIDING GLUTAMINE Abbott Laboratories (US) 2005-07-27 EP disclosed
US-20040081708-A1 Methods and compositions for providing glutamine BAXTER JEFFREY H (US) 2004-04-29 US disclosed
WO-2004032653-A1 METHODS AND COMPOSITIONS FOR PROVIDING GLUTAMINE ABBOTT LABORATORIES (US) 2004-04-22 WO disclosed
US-20030134851-A1 Methods and compositions for providing glutamine BAXTER JEFFREY H (US) 2003-07-17 US disclosed