SCHEMBL24978653

SCHEMBL24978653

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nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
KDM4E B2RXH2 1/20 0.52
THRB P10828 1/20 0.52
ALOX15 P16050 1/20 0.52
NFKB1 P19838 1/20 0.52
PTGS2 P35354 1/20 0.52
THPO P40225 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
ALDH1A1 P00352 2/20 0.50
NOD1 Q9Y239 2/20 0.47
FOLH1 Q04609 5/20 0.47
NAALAD2 Q9Y3Q0 2/20 0.47
RIMKLA Q8IXN7 1/20 0.47
GNPAT O15228 1/20 0.43
ALB P02768 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24978634 1.00 MAPT (0.52) MAPTSMN1; SMN2KDM4ETHRBALOX15
SCHEMBL24978671 1.00 MAPT (0.52) MAPTSMN1; SMN2KDM4ETHRBALOX15
SCHEMBL6445994 0.85 KMT2A (0.53) MAPTSMN1; SMN2KDM4ETHRBALOX15
SCHEMBL13226111 0.85 MAPT (0.52) MAPTSMN1; SMN2KDM4ETHRBALOX15
SCHEMBL15942692 0.85 MAPT (0.52) MAPTSMN1; SMN2KDM4ETHRBALOX15
SCHEMBL19100404 0.83 KDM4E (0.50) MAPTSMN1; SMN2KDM4ETHRBALOX15
SCHEMBL14478726 0.83 NOD1 (0.54) MAPTSMN1; SMN2KDM4ETHRBALOX15
SCHEMBL15451406 0.83 NOD1 (0.54) MAPTSMN1; SMN2KDM4ETHRBALOX15
SCHEMBL19718595 0.83 FOLH1 (0.60) MAPTSMN1; SMN2KDM4ETHRBALOX15
SCHEMBL15451421 0.83 NOD1 (0.54) MAPTSMN1; SMN2KDM4ETHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025037775-A1 COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF DIABETES AND RELATED DISEASES 주식회사 마이크로엑스 2025-02-20 WO disclosed
WO-2024147532-A1 COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF SEPSIS 주식회사 마이크로엑스 2024-07-11 WO disclosed
WO-2023219227-A1 COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING ALZHEIMER'S DISEASE 주식회사 마이크로엑스 2023-11-16 WO disclosed
US-20230026277-A1 COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF RESPIRATORY DISEASE MICROX CO., LTD. (KR) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026277-A1 COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF RESPIRATORY DISEASE RELA, CSNK2A1, CSNK1G1 MAPT 1943/4885SMN1; SMN2 3193/4885KDM4E 4088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.