Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL6446018 | 0.86 | P2RX7 (0.86) | P2RX7 | |
| SCHEMBL5549870 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL5553077 | 0.83 | P2RX7 (1.00) | P2RX7 | |
| Hydrochloric Acid SCHEMBL5552964 | 0.82 | P2RX7 (0.98) | P2RX7 | |
| SCHEMBL5555101 | 0.78 | P2RX7 (0.82) | P2RX7 | |
| SCHEMBL5553043 | 0.78 | P2RX7 (0.82) | P2RX7 | |
| SCHEMBL5553834 | 0.76 | P2RX7 (0.79) | P2RX7 | |
| SCHEMBL5549866 | 0.76 | P2RX7 (0.82) | P2RX7 | |
| SCHEMBL5549877 | 0.76 | P2RX7 (0.82) | P2RX7 | |
| SCHEMBL5553070 | 0.76 | P2RX7 (0.82) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599432-A1 | ADAMANTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | AstraZeneca AB (SE) | 2005-11-30 | — | — | EP | claimed |
| WO-2004074224-A1 | ADAMANTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | claimed |