Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL1377094 | 0.85 | LMNA (0.67) | LMNAALOX15ALDH1A1SOAT1MEN1 | |
| Aminomethylamide SCHEMBL10378627 | 0.84 | LMNA (0.52) | LMNAALOX15SOAT1MEN1FAAH | |
| Acetamide SCHEMBL6279784 | 0.83 | LMNA (0.63) | LMNAALOX15ALDH1A1MEN1CYP1A2 | |
| Carbamic Acid SCHEMBL5387548 | 0.83 | LMNA (0.63) | LMNAALOX15ALDH1A1MEN1CYP1A2 | |
| Butyric Acid SCHEMBL8820913 | 0.82 | FFAR3 (0.59) | LMNAALOX15ALDH1A1MEN1CYP1A2 | |
| SCHEMBL21768046 | 0.82 | LMNA (0.55) | LMNAALDH1A1CES2CES1FFAR3 | |
| Isobutyramide SCHEMBL11523528 | 0.82 | LMNA (0.55) | LMNAALOX15 | |
| SCHEMBL5243851 | 0.82 | LMNA (0.55) | LMNAALOX15ALDH1A1KDM4E | |
| Isobutyramide SCHEMBL2428256 | 0.81 | LMNA (0.60) | LMNAALOX15ALDH1A1MEN1CYP1A2 | |
| Butyramide SCHEMBL8555402 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6084131-A | Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2000-07-04 | — | — | US | claimed |
| EP-1599508-A1 | COPOLYMERS COMPRISING BIOMOLECULES | Novartis AG (CH) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004076500-A1 | COPOLYMERS COMPRISING BIOMOLECULES | NOVARTIS AG (CH) | 2004-09-10 | — | — | WO | disclosed |