SCHEMBL6446183

SCHEMBL6446183

CC(=O)OCCNc1ccc(C)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.55
TDP1 Q9NUW8 1/20 0.46
POLB P06746 1/20 0.44
PTPN1 P18031 1/20 0.43
PKM P14618 1/20 0.43
GAA P10253 2/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KDM4E B2RXH2 1/20 0.42
RECQL P46063 1/20 0.42
DHODH Q02127 1/20 0.41
LMNA P02545 1/20 0.41
NPC1 O15118 1/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
NLRP1 Q9C000 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
FFAR1 O14842 1/20 0.41
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27673633 0.86 MAPT (0.46) MAPTTDP1POLBGAAHTT
SCHEMBL20804140 0.86 ALDH1A1 (0.46) MAPTTDP1POLBGAASMN1; SMN2
SCHEMBL4763640 0.84 SMN1; SMN2 (0.45) MAPTPKMGAASMN1; SMN2KDM4E
SCHEMBL5950512 0.84 KDM4E (0.52) MAPTGAAHTTSMN1; SMN2KDM4E
SCHEMBL13482697 0.83 MAPT (0.48) MAPTTDP1POLBPTPN1PKM
SCHEMBL10126638 0.83 MAPT (0.52) MAPTTDP1POLBPTPN1PKM
SCHEMBL27887836 0.83 GAA (0.61) MAPTPTPN1GAASMN1; SMN2NPC1
SCHEMBL9365801 0.83 POLB (0.47) POLBKDM4ERECQLLMNAKMT2A
Hydrochloric Acid SCHEMBL1066414 0.82 KDM4E (0.51) MAPTGAAHTTSMN1; SMN2KDM4E
SCHEMBL28276814 0.81 TDP1 (0.48) MAPTTDP1POLBGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874105-B Preparation method of visible light and water promoted homoallylic amine compound 大连理工大学 2023-03-03 CN claimed
CN-114874105-A Preparation method of visible light and water promoted homoallylic amine compound 大连理工大学 2022-08-09 CN claimed
CN-114874105-B Preparation method of visible light and water promoted homoallylic amine compound 大连理工大学 2023-03-03 CN disclosed
CN-114874105-B Preparation method of visible light and water promoted homoallylic amine compound 大连理工大学 2023-03-03 CN disclosed
CN-114652699-B Size-transition type nano drug delivery carrier and preparation method and application thereof 华中科技大学 2023-01-03 CN disclosed
CN-114874105-A Preparation method of visible light and water promoted homoallylic amine compound 大连理工大学 2022-08-09 CN disclosed
CN-114874105-A Preparation method of visible light and water promoted homoallylic amine compound 大连理工大学 2022-08-09 CN disclosed
CN-114652699-A Size-transition type nano drug delivery carrier and preparation method and application thereof 华中科技大学 2022-06-24 CN disclosed
EP-0889933-B1 METHODS OF CURING UNSATURATED POLYMERS USING TERTIARY AROMATIC AMINE CURE PROMOTERS ALBEMARLE CORP (US) 2005-05-25 EP disclosed
US-6774193-B2 VINYL ESTER RESIN THAT IS THE REACTION PRODUCT OF POLYEPOXIDE AND AN ETHYLENEICALLY UNSATURATED CARBOXYLIC ACID ALONG WITH A TERTIARY AROMATIC AMINE CURE PROMOTER ALBEMARLE CORPORATION 2004-08-10 US disclosed
US-20030083443-A1 Stabilized unsaturated polymer resin compositions and methods of using the same FIRST CHEMICAL CORPORATION 2003-05-01 US disclosed
US-6258894-B1 Methods of curing unsaturated polymers using tertiary aromatic amine cure promoters FIRST CHEMICAL CORPORATION 2001-07-10 US disclosed
US-6114470-A CROSSLINKABLE COMPOSITION, CONSISTING ESSENTIALLY OF A CROSSLINKABLE UNSATURATED POLYMER RESIN, A PEROXIDE INITIATOR, AND A CURE PROMOTER TERTIARY AROMATIC AMINE FIRST CHEMICAL CORPORATION (US) 2000-09-05 US disclosed
EP-0889933-A1 METHODS OF CURING UNSATURATED POLYMERS USING TERTIARY AROMATIC AMINE CURE PROMOTERS First Chemical Corporation (US) 1999-01-13 EP disclosed
WO-1997035916-A1 METHODS OF CURING UNSATURATED POLYMERS USING TERTIARY AROMATIC AMINE CURE PROMOTERS FIRST CHEMICAL CORPORATION (US) 1997-10-02 WO disclosed