Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 6/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CBR1 | P16152 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681745 | 0.81 | SLC6A2 (0.58) | CHRM1TTRSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL929750 | 0.79 | MEN1 (0.45) | MAPTLMNAHPGD | |
| SCHEMBL5324430 | 0.79 | FFAR1 (0.61) | TTRSLC6A2SLC6A3MAPTNR1I2 | |
| SCHEMBL7186092 | 0.78 | TTR (0.75) | CHRM1TTRSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL30902343 | 0.77 | CYP1A2 (0.52) | MAPTLMNAHPGDTDP1 | |
| SCHEMBL27341302 | 0.77 | CYP1A2 (0.52) | MAPTLMNAHPGDTDP1 | |
| SCHEMBL3507727 | 0.76 | TDP1 (0.43) | MAPTLMNAHSP90AA1HSPA5HPGD | |
| SCHEMBL29439097 | 0.76 | IDO1 (0.54) | LMNATDP1 | |
| SCHEMBL895205 | 0.76 | IDO1 (0.54) | LMNATDP1 | |
| SCHEMBL5759267 | 0.75 | FFAR4 (0.44) | MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320516-B1 | PROCESS FOR THE PREPARATION OF HALOGENATED HYDROXYDIPHENYL COMPOUNDS | CIBA SC HOLDING AG (CH) | 2005-10-05 | — | — | EP | disclosed |
| EP-0857711-B1 | Process for the preparation of halogenated hydroxy diphenyl compounds | CIBA SC HOLDING AG (CH) | 2003-06-04 | — | — | EP | disclosed |
| US-6215029-B1 | ACYLATION OF DICHLOROBENZENE; CATALYTIC ETHERIFICATION WITH CHLORINATED PHENOL IN BASE AND COPPER COMPOUND PRESENCE; OXIDATION, HYDROLYSIS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-04-10 | — | — | US | disclosed |