Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.61 |
| ▸ | TTR | P02766 | 5/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.45 |
| ▸ | CBR1 | P16152 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446133 | 0.81 | MAOB (0.48) | LMNAALDH1A1 | |
| SCHEMBL3438989 | 0.80 | MAPT (0.62) | FFAR1TTRMRGPRX4PNLIPMAPT | |
| SCHEMBL12239005 | 0.80 | FFAR1 (0.60) | FFAR1TTRMRGPRX4MAPTHPGD | |
| SCHEMBL9265274 | 0.80 | TTR (0.65) | FFAR1TTRMRGPRX4PNLIPMAPT | |
| SCHEMBL4414860 | 0.80 | FFAR1 (0.60) | FFAR1TTRMAPTHPGDNR1I2 | |
| SCHEMBL4704919 | 0.80 | PDE7A (0.67) | MAPTHPGDLMNAKDM4EMEN1 | |
| SCHEMBL6446286 | 0.79 | CHRM1 (0.52) | TTRMAPTHPGDNR1I2LMNA | |
| SCHEMBL25048634 | 0.78 | HTR2A (0.43) | FFAR1PNLIPMAPTHPGDKDM4E | |
| SCHEMBL9036833 | 0.78 | FFAR1 (0.74) | FFAR1TTRMRGPRX4NR3C1 | |
| SCHEMBL8502158 | 0.78 | FFAR1 (0.56) | FFAR1TTRMRGPRX4PNLIPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |
| WO-2007110209-A1 | BIOLOGICAL MATERIALS AND USES THEREOF | BIOINVENT INTERNATIONAL AB (SE) | 2007-10-04 | — | — | WO | disclosed |