Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574409 | 0.81 | KCNH2 (1.00) | HRH3KCNH2 | |
| SCHEMBL9102223 | 0.81 | HRH3 (0.71) | HRH3KCNH2 | |
| SCHEMBL9105208 | 0.78 | HRH3 (0.66) | HRH3KCNH2 | |
| SCHEMBL9104832 | 0.72 | HRH3 (0.69) | HRH3KCNH2 | |
| SCHEMBL1574571 | 0.71 | KCNH2 (1.00) | HRH3KCNH2 | |
| SCHEMBL9101614 | 0.71 | HRH3 (0.69) | HRH3KCNH2 | |
| SCHEMBL1640161 | 0.70 | HRH3 (0.68) | HRH3KCNH2 | |
| SCHEMBL9105288 | 0.69 | HRH3 (0.57) | HRH3KCNH2 | |
| SCHEMBL1641335 | 0.69 | KCNH2 (1.00) | HRH3KCNH2 | |
| SCHEMBL1574289 | 0.69 | KCNH2 (1.00) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256118-A1 | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents | ABBOTT LABORATORIES | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256118-A1 | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents | HRH3, HRH4, HRH2 | HRH3 1/4885KCNH2 667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.