Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574332 | 0.79 | KCNH2 (1.00) | HRH3KCNH2 | |
| SCHEMBL9101378 | 0.79 | HRH3 (0.68) | HRH3KCNH2 | |
| SCHEMBL6446409 | 0.78 | HRH3 (0.68) | HRH3KCNH2 | |
| SCHEMBL1639515 | 0.65 | KCNH2 (1.00) | HRH3KCNH2 | |
| SCHEMBL1640942 | 0.62 | HRH3 (0.66) | HRH3KCNH2 | |
| SCHEMBL1574345 | 0.62 | KCNH2 (1.00) | HRH3KCNH2 | |
| SCHEMBL489011 | 0.61 | HRH3 (0.52) | HRH3KCNH2 | |
| SCHEMBL489012 | 0.61 | HRH3 (0.52) | HRH3KCNH2 | |
| SCHEMBL24568821 | 0.61 | HRH3 (0.47) | HRH3KCNH2 | |
| SCHEMBL24568812 | 0.61 | HRH3 (0.47) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751149-B1 | BICYCLIC-SUBSTITUTED AMINES HAVING CYCLIC-SUBSTITUTED MONOCYCLIC SUBSTITUENTS | ABBOTT LAB (US) | 2012-06-06 | — | — | EP | disclosed |