Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 6/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422603 | 0.95 | HDAC3 (0.37) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL14771635 | 0.87 | LMNA (0.41) | GAALMNASMN1; SMN2 | |
| SCHEMBL12824669 | 0.87 | LMNA (0.41) | GAALMNASMN1; SMN2 | |
| SCHEMBL8422238 | 0.87 | LMNA (0.41) | GAALMNASMN1; SMN2 | |
| SCHEMBL9474731 | 0.86 | HSD17B10 (0.39) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL4270532 | 0.82 | HDAC3 (0.42) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9621819 | 0.81 | HDAC3 (0.44) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL10606260 | 0.81 | HDAC3 (0.36) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17995 | 0.79 | HDAC3 (0.36) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7621151 | 0.79 | HDAC3 (0.37) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594910-A1 | PROCESS FOR PREPARING A MELT-PROCESSABLE POLYAMIDE COMPOSITION | DSM IP Assets B.V. (NL) | 2005-11-16 | — | — | EP | disclosed |
| EP-1594911-A1 | PROCESS FOR PREPARING A MELT-PROCESSABLE POLYAMIDE COMPOSITION | DSM IP Assets B.V. (NL) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004074348-A1 | PROCESS FOR PREPARING A MELT-PROCESSABLE POLYAMIDE COMPOSITION | DSM IP ASSETS B.V. (NL) | 2004-09-02 | — | — | WO | disclosed |
| WO-2004074347-A1 | PROCESS FOR PREPARING A MELT-PROCESSABLE POLYAMIDE COMPOSITION | DSM IP ASSETS B.V. (NL) | 2004-09-02 | — | — | WO | disclosed |