Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446681 | 1.00 | PARP1 (0.34) | PARP1L3MBTL1C5AR1KDM4CLTB4R2 | |
| SCHEMBL6443103 | 0.83 | L3MBTL1 (0.42) | PARP1L3MBTL1KDM4EDPP4DPP9 | |
| SCHEMBL6442488 | 0.79 | CYP2C19 (0.48) | PARP1L3MBTL1 | |
| SCHEMBL6442483 | 0.79 | CYP2C19 (0.48) | PARP1L3MBTL1 | |
| SCHEMBL6442520 | 0.72 | CYP2C9 (0.50) | PARP1KDM4E | |
| SCHEMBL6445472 | 0.70 | L3MBTL1 (0.40) | PARP1L3MBTL1DPP4DPP9 | |
| SCHEMBL6442530 | 0.70 | L3MBTL1 (0.43) | PARP1L3MBTL1KDM4EDPP4DPP9 | |
| SCHEMBL6442848 | 0.68 | CYP2C19 (0.55) | PARP1 | |
| SCHEMBL6442845 | 0.68 | CYP2C19 (0.55) | PARP1 | |
| SCHEMBL6441836 | 0.68 | L3MBTL1 (0.41) | PARP1L3MBTL1DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299382-B1 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED INDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2005-09-21 | — | — | EP | claimed |