Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429324 | 0.87 | MEN1 (0.49) | MEN1KMT2AUSP30UCHL1MAPT | |
| SCHEMBL2158008 | 0.86 | MEN1 (0.52) | MEN1KMT2AUSP30NPSR1GPR119 | |
| SCHEMBL6431276 | 0.84 | ACKR3 (0.43) | MEN1KMT2AUSP30UCHL1ALDH1A1 | |
| SCHEMBL3808918 | 0.83 | MEN1 (0.37) | MEN1KMT2AUSP30UCHL1ALDH1A1 | |
| SCHEMBL6426599 | 0.83 | USP30 (0.47) | MEN1KMT2AUSP30MAPTACKR3 | |
| SCHEMBL2158431 | 0.82 | ALDH1A1 (0.44) | ALDH1A1LMNATSHR | |
| SCHEMBL6446820 | 0.82 | MEN1 (0.35) | MEN1KMT2AUSP30UCHL1ALDH1A1 | |
| SCHEMBL2157741 | 0.81 | ALDH1A1 (0.42) | ALDH1A1LMNATSHR | |
| SCHEMBL3814854 | 0.81 | MEN1 (0.39) | MEN1KMT2AUSP30RXRANR1H2 | |
| SCHEMBL3811287 | 0.80 | MEN1 (0.34) | MEN1KMT2AUSP30UCHL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881741-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC. (CA) | 2005-04-19 | — | — | US | claimed |