Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | FGF2 | P09038 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062550 | 0.82 | GRIN2D (0.57) | GRIN1GRIN2BGPBAR1LMNASRD5A2 | |
| SCHEMBL19260808 | 0.82 | GRIN2D (0.57) | GRIN1GRIN2BGPBAR1LMNASRD5A2 | |
| SCHEMBL4726566 | 0.80 | CYP19A1 (0.56) | GPBAR1LMNAMAPTABCC4 | |
| SCHEMBL4927255 | 0.80 | CYP19A1 (0.56) | GPBAR1LMNAMAPTABCC4 | |
| SCHEMBL11411828 | 0.74 | GPBAR1 (0.52) | GPBAR1LMNASRD5A2CYP17A1MAPT | |
| SCHEMBL15796049 | 0.73 | GRIN1 (0.87) | GRIN1GRIN2BGPBAR1LMNAABCC4 | |
| SCHEMBL2392476 | 0.73 | GRIN1 (0.87) | GRIN1GRIN2BGPBAR1LMNAABCC4 | |
| SCHEMBL2392478 | 0.73 | GRIN1 (0.87) | GRIN1GRIN2BGPBAR1LMNAABCC4 | |
| SCHEMBL15994082 | 0.73 | GRIN1 (0.87) | GRIN1GRIN2BGPBAR1LMNAABCC4 | |
| SCHEMBL3121228 | 0.72 | GPBAR1 (0.69) | GPBAR1LMNASRD5A2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050042268-A1 | Pharmaceutical composition and method for transdermal drug delivery | PERRIGO ISRAEL PHARMACEUTICALS LTD. (IL) | 2005-02-24 | — | — | US | disclosed |