Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447697 | 1.00 | AKR1C3 (0.46) | AKR1C3LMNAMEN1KMT2ATDP1 | |
| SCHEMBL525211 | 0.78 | AKR1C3 (0.55) | AKR1C3LMNAMEN1KMT2ATDP1 | |
| SCHEMBL525210 | 0.78 | AKR1C3 (0.55) | AKR1C3LMNAMEN1KMT2ATDP1 | |
| SCHEMBL30466153 | 0.78 | LMNA (0.49) | AKR1C3LMNAMEN1KMT2ATDP1 | |
| SCHEMBL11528100 | 0.74 | TDP1 (0.48) | AKR1C3LMNAMEN1KMT2ATDP1 | |
| SCHEMBL1524596 | 0.74 | ELANE (0.33) | LMNAMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL28349681 | 0.74 | KMT2A (0.50) | AKR1C3MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL2774413 | 0.74 | AKR1C3 (0.50) | AKR1C3MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL225383 | 0.72 | AKR1C3 (0.57) | AKR1C3LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL7593618 | 0.72 | MEN1 (0.43) | AKR1C3LMNAMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551885-A2 | PROCESS TO MODIFY POLYMERIC MATERIALS AND RESULTING COMPOSITIONS | 3M Innovative Properties Company (US) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004013189-A2 | PROCESS TO MODIFY POLYMERIC MATERIALS AND RESULTING COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-02-12 | — | — | WO | disclosed |