Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500848 | 0.82 | KMT2A (0.43) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL11038944 | 0.79 | TYR (0.46) | HTTNPSR1ESR1ESR2TP53 | |
| SCHEMBL30628000 | 0.79 | TSHR (0.50) | HTTESR1ESR2CYSLTR2CYSLTR1 | |
| SCHEMBL177521 | 0.79 | TSHR (0.50) | HTTESR1ESR2CYSLTR2CYSLTR1 | |
| SCHEMBL28530459 | 0.78 | TYR (0.44) | HTTESR1ESR2TP53ALOX15 | |
| SCHEMBL5422365 | 0.77 | TSHR (0.48) | HTTESR1ESR2CYSLTR2CYSLTR1 | |
| SCHEMBL10707896 | 0.77 | CYSLTR2 (0.36) | ESR1ESR2ADRB2TYRCYSLTR2 | |
| SCHEMBL7755498 | 0.77 | PDE5A (0.42) | HTTNPC1MAPK1RAB9ANPSR1 | |
| SCHEMBL2947212 | 0.76 | BCHE (0.41) | HTTHPGDESR1ESR2ALOX15 | |
| SCHEMBL11036500 | 0.76 | TYR (0.45) | HTTESR1TP53ALOX15CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050214529-A1 | Acrylic block copolymer and uses thereof | NIPPON SHOKUBAI CO., LTD. | 2005-09-29 | — | — | US | disclosed |
| EP-1580202-A1 | Acrylic block copolymer and uses thereof | Nippon Shokubai Co., Ltd. (JP) | 2005-09-28 | — | — | EP | disclosed |