Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 8/20 | 0.41 |
| ▸ | HTR2B | P41595 | 7/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | BPTF | Q12830 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27862879 | 0.98 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL988610 | 0.78 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL1028438 | 0.78 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL644788 | 0.78 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL17884678 | 0.78 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL2975110 | 0.78 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL710615 | 0.78 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL2454158 | 0.78 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| SCHEMBL17884836 | 0.78 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 | |
| Bromide SCHEMBL10498800 | 0.76 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3ADRB1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221612-A | Preparation method of l- [2- (2, 4-dimethylbenzenesulfide) -phenyl ] piperazine halogen acid salt | 浙江华海药业股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-107501299-A | The simultaneously carboxamides derivatives of [3,2 a] pyrimidine 2 and the application of 5,7 diphenyl 5H thiazoles | 石家庄学院 | 2017-12-22 | — | — | CN | disclosed |
| CN-107235994-A | The simultaneously acetamide derivative of [3,2 a] pyrimidine 3 and the application of 5,7 diphenyl 5H thiazoles | 石家庄学院 | 2017-10-10 | — | — | CN | disclosed |
| EP-1075469-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-02-14 | — | — | EP | disclosed |
| WO-2000052001-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-09-08 | — | — | WO | disclosed |